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        397-408 of 684 results for 'early intervention'

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        Assessment of early lung disease in young children with CF: A comparison between pressure-controlled and free-breathing chest computed tomography

        Our data suggest that FRC PC-CTs are less sensitive than TLC PC-CTs and that FB-CTs have similar sensitivity to PC-CTs in detecting lung disease ...

        Research

        The challenges of developing and optimising an assay to measure 25-hydroxyvitamin D in saliva

        We have developed an LC-MS/MS assay that accurately measures saliva 25(OH)D3 levels, which correlated with serum levels ...

        Research

        Water Quality and the Microbiome Study (TUMS): The effects of chlorinated drinking water on the assembly of the infant gut microbiome

        David Debbie Desiree Matt Susan Martino Palmer Silva Cooper Prescott DM D DS MC SL BSc PhD BSc BND PhD MBBS, FRACP, MPH, PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD MBBS BMedSci PhD FRACP Head, Clinical Epigenetics Head, Early Life ...

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        Regular exercise improves the well-being of parents of children with cancer

        Mental health benefits of a pedometer-based exercise intervention for parents of children with cancer were identified. ...

        Research

        Is autism one or multiple disorders?

        Elucidating the underlying nature of the disorder(s) is a crucial step towards tailoring intervention to the biological and cognitive makeup of each individual. ...

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        Group mindful self-compassion training to improve mental health outcomes for LGBTQIA+ young adults: Rationale and protocol for a randomised controlled trial

        Young adults who are lesbian, gay, bisexual, trans, queer or questioning, intersex, asexual and other diverse genders and sexualities (LGBTQIA+) are more likely to experience mental health difficulties and are at significantly elevated risk of substance abuse, self-harm and suicide, relative to their heterosexual, endosex and cisgender peers. There is a need for effective mental health interventions for LGBTQIA+ young adults. Mindful Self-Compassion training is a promising approach; among LGBTQIA+ individuals, self-compassion accounts for more variation in mental health outcomes than bullying, victimization, and adverse childhood experiences combined. Furthermore, LGBTQIA+ individuals with high self-compassion report more positive identity and happiness, less self-stigma, and lower suicidality than those with low self-compassion. ...

        Research

        PREDICT CF: Assessing the role of lung clearance index in predicting disease progression in children with cystic fibrosis

        Stephen Graham Elizabeth Stick Hall Smith SM GL ES MB BChir PhD MRCP FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS PhD, MSc, BSc Head, P4 Respiratory Health for Kids Honorary Research Associate Program Manager 08 6319 1178 elizabeth.smith@ ...

        Research

        BEAT CF pulmonary exacerbations core protocol for evaluating the management of pulmonary exacerbations in people with cystic fibrosis

        Cystic fibrosis (CF) is a rare, inherited, life-limiting condition predominantly affecting the lungs, for which there is no cure. The disease is characterized by recurrent pulmonary exacerbations (PEx), which are thought to drive progressive lung damage. Management of these episodes is complex and generally involves multiple interventions targeting different aspects of disease. The emergence of innovative trials and use of Bayesian statistical methods has created renewed opportunities for studying heterogeneous populations in rare diseases. ...

        Research

        BEAT-CF: Bayesian Evidence-Adaptive Tool to optimise management of Cystic Fibrosis

        Stephen André Stick Schultz SM AS MB BChir PhD MRCP FRACP MBChB, PhD, FRACP Head, P4 Respiratory Health for Kids Program Head, Respiratory Health RFA Head, P4 Respiratory Health for Kids Program Head, Respiratory Health RFA Areas for research ...

        Research

        DEFEND CF: Biomarkers to define the treatment end-point for pulmonary exacerbations in cystic fibrosis

        Stephen Graham Stick Hall SM GL MB BChir PhD MRCP FRACP BAppSci PhD CRFS FANZSRS FThorSoc FERS Head, P4 Respiratory Health for Kids Honorary Research Associate Head, P4 Respiratory Health for Kids Honorary Research Associate Areas for research ...

        Research

        Developing a novel therapeutic pipeline for antibiotic resistant bacterial lung infection in children: investigating and assessing the potential phage therapy

        Anthony Stephanie Stephen Kicic Trend Stick A ST SM BSc (Hons) PhD BSc PhD MB BChir PhD MRCP FRACP Rothwell Family Fellow; Head, Airway Epithelial Research Honorary Research Associate Head, P4 Respiratory Health for Kids 6319 1430 Anthony.Kicic@ ...

        Research

        Innate inflammatory responses of pediatric cystic fibrosis airway epithelial cells: Effects of nonviral and viral stimulation

        There is controversy regarding whether cystic fibrosis (CF) airway epithelial cells (AECs) are intrinsically proinflammatory. ...

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