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        “Broken fragments or a breathtaking mosaic”: A mixed methods study of self-reported attributes and aspirations of siblings of individuals with and without neurodevelopmental conditions

        Siblings of individuals with neurodevelopmental conditions (NDCs) experience distinct challenges and have unique strengths compared to siblings of individuals without NDCs. ...

        Research

        Safety, tolerability, and effect of a single aural dose of Dornase alfa at the time of ventilation tube surgery for otitis media: A Phase 1b double randomized control trial

        One third of children require repeat ventilation tube insertion (VTI) for otitis media. Disease recurrence is associated with persistent middle ear bacterial biofilms. With demonstration that Dornase alfa (a DNase) disrupts middle ear effusion biofilms ex vivo, we identified potential for this as an anti-biofilm therapy to prevent repeat VTI. First, safety and tolerability needed to be measured. ...

        Research

        A systematic review of the biological, social, and environmental determinants of intellectual disability in children and adolescents

        This systematic review aimed to identify the most important social, environmental, biological, and/or genetic risk factors for intellectual disability. ...

        Research

        Daytime sleepiness and emotional and behavioral disturbances in Prader-Willi syndrome

        Individuals with Prader-Willi syndrome (PWS) often have excessive daytime sleepiness and emotional/behavioral disturbances. The objective of this study was to examine whether daytime sleepiness was associated with these emotional/behavioral problems, independent of nighttime sleep-disordered breathing, or the duration of sleep. ...

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        Association between craniofacial anomalies, intellectual disability and autism spectrum disorder: Western Australian population-based study

        Accurate knowledge of the relationship between craniofacial anomalies (CFA), intellectual disability (ID) and autism spectrum disorder (ASD) is essential to improve services and outcomes. The aim is to describe the association between CFA, ID and ASD using linked population data. ...

        Research

        Dental procedures in children with or without intellectual disability and autism spectrum disorder in a hospital setting

        This population-based cohort study investigated dental procedures in the hospital setting in Western Australian children with or without intellectual disability (ID) and/or autism spectrum disorder (ASD) aged up to 18 years. ...

        Research

        Employing cognitive interviewing to evaluate, improve and validate items for measuring the health-related quality of life of women diagnosed with ovarian cancer

        Use of patient-reported outcome measures in clinical settings facilitate the delivery of better health care to improve patient health outcomes. ...

        Research

        Trends in prenatal diagnosis of congenital anomalies in Western Australia between 1980 and 2020: A population-based study

        Advances in screening and diagnostics have changed the way in which we identify and diagnose congenital anomalies. ...

        Research

        Continuous electroencephalography in the intensive care unit: A critical review and position statement from an Australian and New Zealand perspective

        This article aims to critically review the literature on continuous electroencephalography (cEEG) monitoring in the intensive care unit (ICU) from an Australian and New Zealand perspective and provide recommendations for clinicians. Design and review methods: A taskforce of adult and paediatric neurologists, selected by the Epilepsy Society of Australia, reviewed the literature on cEEG for seizure detection in critically ill neonates, children, and adults in the ICU. ...

        Research

        Association between ABO, Rh blood groups, lip and dermatoglyphic patterns, and nonsyndromic oral clefts: A case-control study

        The objective of the study is to determine the association between nonsyndromic oral clefts (OC) in children and ABO, Rh blood groups, lip, and dermatoglyphic patterns of their unaffected parents. ...

        Research

        Assessing the quality, efficiency and usefulness of the Western Australian population-based Intellectual Disability Exploring Answers (IDEA) surveillance system

        The IDEA system is a valuable resource to address the needs of people living with intellectual disability ...

        Research

        The Brain Basis of Comorbidity in Neurodevelopmental Disorders

        This review discusses early brain development and the etiological factors that may give rise to atypical developmental trajectories, along with neuroimaging insights ...

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