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        Reduction in hypoglycemia with the predictive low-Glucose management system: A long-term randomized controlled trial in adolescents with type 1 diabetes

        Short-term studies with automated systems that suspend insulin when hypoglycemia is predicted have shown a reduction, but safety and efficacy aren't established ...

        Research

        Pre-onset risk characteristics for mania among young people at clinical high risk for psychosis

        We aimed to identify the rate and predictors of transition to mania in a cohort of youth with clinical or familial risk for psychosis. ...

        Research

        Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children

        We characterized the lower airways microbiome using BAL samples obtained from clinically stable CF young children who underwent bronchoscopy and chest CT. ...

        Research

        Are scabies and impetigo “normalised”? A cross-sectional comparative study of hospitalised children in northern Australia assessing clinical recognition

        Scabies and impetigo infections are under-recognised and hence under-treated by clinicians ...

        Research

        Randomized controlled trial of early regular egg intake to prevent egg allergy

        We aimed to determine whether regular consumption of egg protein from 4-6 month old reduced the risk of IgE-mediated egg allergy in infants without eczema. ...

        Research

        Repeat pneumococcal polysaccharide vaccine in Indigenous Australian adults is associated with decreased immune responsiveness

        These findings highlight the critical need to evaluate the efficacy of future pneumococcal vaccine programs in the Australian Indigenous populations that recommend repeated doses of 23vPPV. ...

        Research

        Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

        The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average. ...

        Research

        A novel technique of serial biopsy in mouse brain tumour models

        Here we describe a method by which serial biopsy can be used to validate response to dacomitinib treatment in vivo using a mouse glioblastoma model ...

        Research

        Sub-erythemal ultraviolet radiation reduces metabolic dysfunction in already overweight mice

        Exposure to sunlight may limit cardiometabolic risk. ...

        Research

        International consensus (ICON) on: Clinical consequences of mite hypersensitivity, a global problem

        The objectives of this document are to highlight aspects of mite biology that are clinically relevant and to update the current knowledge on mite allergens ...

        Research

        What is the evidence for managing tone in young children with, or at risk of developing, cerebral palsy: a systematic review

        To conduct a systematic review of the evidence for the management of tone in infants 0-24 months of age, with or at risk of developing cerebral palsy. ...

        Research

        Associations of Early- and Later-Childhood Poverty with Child Cognitive Function in Indonesia: Effect Decomposition in the Presence of Exposure-Induced Mediator-Outcome Confounding

        Our analysis shows that early and late intervention to support household income have equal importance with regards to significance of impact. ...

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