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        421-432 of 3475 results for 'development'

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        Maps and metrics of insecticide-treated net access, use, and nets-per-capita in Africa from 2000-2020

        Insecticide-treated nets (ITNs) are one of the most widespread and impactful malaria interventions in Africa, yet a spatially-resolved time series of ITN coverage has never been published. Using data from multiple sources, we generate high-resolution maps of ITN access, use, and nets-per-capita annually from 2000 to 2020 across the 40 highest-burden African countries. ...

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        Gut microbiota and metabolomics profiles in patients with chronic stable angina and acute coronary syndrome

        Cardiovascular disease is the leading cause of death worldwide. The gut microbiota and its associated metabolites may be involved in the development and progression of CVD, although the mechanisms and impact on clinical outcomes are not fully understood. This study investigated the gut microbiome profile and associated metabolites in patients with chronic stable angina and acute coronary syndrome compared with healthy controls. ...

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        Target identification for small-molecule discovery in the FOXO3a tumor-suppressor pathway using a biodiverse peptide library

        Genetic screening technologies to identify and validate macromolecular interactions (MMIs) essential for complex pathways remain an important unmet need for systems biology and therapeutics development. Here, we use a library of peptides from diverse prokaryal genomes to screen MMIs promoting the nuclear relocalization of Forkhead Box O3 (FOXO3a), a tumor suppressor more frequently inactivated by post-translational modification than mutation. ...

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        Enteral Vitamin A for Reducing Severity of Bronchopulmonary Dysplasia: A Randomized Trial

        Evidence suggests that intramuscular vitamin A reduces the risk of bronchopulmonary dysplasia (BPD) in preterm infants. Our objective was to compare enteral water-soluble vitamin A with placebo supplementation to reduce the severity of BPD in extremely preterm infants. ...

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        Indigenous young people's resilience and wellbeing

        Carrington Shepherd CCJ PhD Honorary Research Associate Honorary Research Associate Areas of research expertise: Population health; Aboriginal and Torres Strait Islander health; Social inequalities in health; child mortality. Carrington is a Senior ...

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        Targeting cross-presentation as a route to improve the efficiency of peptide-based cancer vaccines

        Cross-presenting dendritic cells (DC) offer an attractive target for vaccination due to their unique ability to process exogenous antigens for presentation on MHC class I molecules. Recent reports have established that these DC express unique surface receptors and play a critical role in the initiation of anti-tumor immunity, opening the way for the development of vaccination strategies specifically targeting these cells. ...

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        Vitamin A and bronchopulmonary dysplasia: the next steps

        Preterm infants are often vitamin A deficient, and vitamin A has functions that could mitigate the processes that lead to bronchopulmonary dysplasia. Therefore, supplementation of preterm infants with vitamin A to reduce the risk of bronchopulmonary dysplasia makes inherent sense. ...

        Research

        Wellbeing and academic achievement paper

        Tess Neida Zara Gregory Sechague Monroy Boulton TG NSM ZB BSc (Hons), PhD (Psychology) BDS, MPH BPsych (Hons) Senior Research Fellow Research Assistant Research Assistant; Gender, Equity, Diversity and Inclusivity Advisor +61 8 6375 6113 0863756104 ...

        Research

        Associations between School Readiness and Student Wellbeing: A Six-Year Follow Up Study

        It is well established that children’s school readiness is associated with their later academic achievement, but less is known about whether school readiness is also associated with other measures of school success, such as students’ social and emotional wellbeing. While some previous research has shown a link between early social and emotional development and student wellbeing, results are mixed and the strength of these relationships vary depending on whether data is based on child, teachers or parents ratings and which specific student wellbeing outcomes are measured. ...

        Research

        Movement behavior policies in the early childhood education and care setting: An international scoping review

        Meeting 24-h movement behavior guidelines for the early years is associated with better health and development outcomes in young children. Early childhood education and care (ECEC) is a key intervention setting however little is known about the content and implementation of movement behavior polices in this context. To inform policy development this international scoping review examined the prevalence, content, development and implementation of ECEC-specific movement behavior policies. ...

        Research

        Developing national guidelines for intervention with children on the autism spectrum in Australia

        Investigators: Prof Andrew Whitehouse, Prof David Trembath Project description This project involves developing a national practice guideline for supporting the development and participation of children on the autism spectrum and their families. The ...

        Research

        Analysis of gender differences between boys and girls in South Australia

        Yasmin Tess Harman-Smith Gregory YHS TG BA, BHlthSc(Hons), PhD BSc (Hons), PhD (Psychology) Head, Early Years Systems Evidence; Head, Tenders Support Unit Senior Research Fellow +61 8 6375 6113 Yasmin.harman-smith@telethonkids.org.au tess.gregory@ ...

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