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        Application of Gene Expression Trajectories Initiated from ErbB Receptor Activation Highlights the Dynamics of Divergent Promoter Usage

        This study helps us understand how cancer cells are regulated by key genes and their corresponding networks to alter their fate in response to specific... ...

        Research

        A novel BRD4-NUT fusion in an undifferentiated sinonasal tumor highlights alternative splicing as a contributing oncogenic factor in NUT midline carcinoma

        In this study, we report the case of an adolescent NMC patient presenting with severe facial pain, proptosis and visual impairment due to a mass arising from... ...

        Research

        GFP-complementation assay to detect functional CPP and protein delivery into living cells.

        Efficient cargo uptake is essential for cell-penetrating peptide (CPP) therapeutics, which deliver widely diverse cargoes by exploiting natural cell... ...

        Research

        A validation study of a modified Bouchard activity record that extends the concept of 'uptime' to Rett syndrome

        The aim of this study was to investigate the validity of using a Bouchard activity record (BAR) in individuals with Rett syndrome to measure physical... ...

        Research

        Patterns of depressive symptoms and social relating behaviors differ over time from other behavioral domains for young people with Down syndrome

        People with intellectual disabilities are at a higher risk for experiencing behavioral, emotional, and psychiatric problems in comparison with the general... ...

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        Can skin exposure to sunlight prevent liver inflammation?

        Here we discuss how skin exposure to sunlight may suppress liver inflammation and the severity of NAFLD. ...

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        Mechanisms of allergic disease - environmental and genetic determinants for the development of allergy

        Environmental exposures including maternal inflammation, diet, nutrient balance, microbial colonization and toxin exposures can directly and indirectly... ...

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        Older maternal age and child behavioral and cognitive outcomes: A review of the literature.

        Although the physical consequences for offspring in utero and in the prenatal period are well known, the psychologic consequences of older motherhood for... ...

        Research

        What works in preventing suicide in Aboriginal and Torres Strait Islander Communities: preliminary findings

        Suicide, suicide ideation and self-harm are critically important public health issues for Aboriginal and Torres Strait Islander communities. ...

        Research

        Childhood atopy and mental health: a prospective, longitudinal investigation

        Findings are the first linking atopy (measured by both parent report and objective verification) with increased vulnerability to affective and anxiety problems ...

        Research

        Commentary: Are we expecting too much from the extreme male brain theory of autism? A reflection on Kung et al. (2016)

        This commentary highlights inconsistent findings that undermine the extreme male brain theory autism but data may not present an adequate test of the hypothesis ...

        Research

        Reactive aggression in young patients with ADHD—a critical role for small provocations

        ADHD is one of the most commonly diagnosed disorders in child and adolescent psychiatry and is characterized by attentional deficits, hyperactivity, and impulsivity ...

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