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        433-444 of 1238 results for '2010'

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        Hesitant compliers': Qualitative analysis of concerned fully-vaccinating parents

        Parents interpreted pivotal vaccine-related events in the community as requiring them to take personal responsibility for vaccine decisions ...

        Research

        Agreement between units of measure for paediatric antibiotic utilisation surveillance using hospital pharmacy supply data

        Agreement between the DDD and vial-based measures of use supports the use of DDD for select antibiotics that may be targeted by antimicrobial stewardship programs ...

        Research

        Immunogenicity and Safety of Monovalent Acellular Pertussis Vaccine at Birth: A Randomized Clinical Trial

        The monovalent acellular pertussis vaccine is immunogenic and safe in neonates ...

        Research

        Maternal Child Health and Wellbeing in the Western Desert

        Carrington Shepherd CCJ PhD Honorary Research Associate Honorary Research Associate Areas of research expertise: Population health; Aboriginal and Torres Strait Islander health; Social inequalities in health; child mortality. Carrington is a Senior ...

        Research

        Skin health situational analysis to inform skin disease control programs for the Kimberley

        Asha Bowen AC BA MBBS DCH FRACP PhD GAICD OAM Head, Healthy Skin and ARF Prevention Head, Healthy Skin and Arf Prevention Areas of expertise: Skin infections, clinical trials, Streptococcus pyogenes, Staphylococcus aureus, Aboriginal children, COVID ...

        Research

        Earth dreams: Reimagining ARPA for health of people, places and planet

        Bold new approaches are urgently needed to overcome global health challenges. The proposed Advanced Research Projects Agency for Health (ARPA-H) is intended to provide rapid health breakthroughs. ...

        Research

        Probiotic peanut oral immunotherapy versus oral immunotherapy and placebo in children with peanut allergy in Australia (PPOIT-003): a multicentre, randomised, phase 2b trial

        Oral immunotherapy is effective at inducing desensitisation to allergens and induces sustained unresponsiveness (ie, clinical remission) in a subset of patients, but causes frequent reactions. We aimed to investigate whether addition of a probiotic adjuvant improved the efficacy or safety of peanut oral immunotherapy. ...

        Research

        Characterization of the transient deficiency of pkc isozyme levels in immature cord blood t cells and its connection to anti‐allergic cytokine profiles of the matured cells

        Cord blood T cells (CBTC) from a proportion of newborns express low/deficient levels of some protein kinase C (PKC) isozymes, with low levels of PKCζ correlating with increased risk of developing allergy and associated decrease in interferon‐gamma (IFN‐γ) producing T cells. ...

        Research

        Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and Planet

        Global food systems are a central issue for personal and planetary health in the Anthropocene. One aspect of major concern is the dramatic global spread of ultra-processed convenience foods in the last 75 years, which is linked with the rising human burden of disease and growing sustainability and environmental health challenges. ...

        Research

        PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensity

        A significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined. ...

        Research

        Ca-EDTA restores the activity of ceftazidime-avibactam or aztreonam against carbapenemase-producing Klebsiella pneumoniae infections

        Developing an effective therapy to overcome carbapenemase-positive Klebsiella pneumoniae (CPKp) is an important therapeutic challenge that must be addressed urgently. Here, we explored a Ca-EDTA combination with aztreonam or ceftazidime-avibactam in vitro and in vivo against diverse CPKp clinical isolates. ...

        Research

        Vitality Revisited: The Evolving Concept of Flourishing and Its Relevance to Personal and Public Health

        Human flourishing, the state of optimal functioning and well-being across all aspects of an individual's life, has been a topic of philosophical and theological discussion for centuries. In the mid-20th century, social psychologists and health scientists began exploring the concept of flourishing in the context of health and high-level wellness. ...

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