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        Exposure to Solar UVR Suppresses Cell-Mediated Immunization Responses in Humans: The Australian Ultraviolet Radiation and Immunity Study

        Higher UVR exposure at antigen sensitization was associated with a reduced delayed-type hypersensitivity response and altered T helper type 17 kinetics ...

        Research

        A Novel Missense Mutation Affecting the N-terminal Domain of SAP Protein in X-linked Lymphoproliferative Disease

        We have revealed a novel SH2D1A gene mutation in a patient with XLP resulting in fulminant refractory EBV-driven HLH, which is a recognized severe complication ...

        Research

        The impact of pre-pregnancy body mass index and gestational weight gain on placental abruption risk: a systematic review and meta-analysis

        Mothers that are underweight prior to or in early pregnancy are at a moderately increased risk of placental abruption ...

        Research

        Autism-related dietary preferences mediate autism-gut microbiome associations

        There is increasing interest in the potential contribution of the gut microbiome to autism spectrum disorder (ASD). However, previous studies have been underpowered and have not been designed to address potential confounding factors in a comprehensive way. ...

        Research

        Methotrexate-related central neurotoxicity: clinical characteristics, risk factors and genome-wide association study in children treated for acute lymphoblastic leukemia

        Symptomatic methotrexate-related central neurotoxicity (MTX neurotoxicity) is a severe toxicity experienced during acute lymphoblastic leukemia (ALL) therapy with potential long-term neurologic complications. Risk factors and long-term outcomes require further study. ...

        Research

        The Proactive Study

        Andrew Gail Whitehouse Watch and listen to Andrew Alvares AJ GA PhD PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids and University of Western Australia; Director, CliniKids Senior Research Fellow 08 6319 1698 ...

        Research

        Two methods for engaging with the community in setting priorities for child health research: Who engages?

        The Western Australian Telethon Kids Institute Participation Program employs a range of methods for fostering active involvement of community members in its... ...

        Research

        Playgroup participation and social support outcomes for mothers of young children: A longitudinal cohort study.

        This study aimed to examine friendship networks and social support outcomes for mothers according to patterns of playgroup participation. ...

        Research

        Maternal smoking and low family income during pregnancy as predictors of the relationship between depression and adiposity in young adults

        We aimed to investigate the influence of antenatal and postnatal factors on the increasing incidence of overweight/obesity and mental health disorders in young adults ...

        Research

        ERS technical standard on bronchial challenge testing: General considerations and performance of methacholine challenge tests

        This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. ...

        Research

        High-dose intramuscular Vitamin D provides long-lasting moderate increases in serum 25-hydroxVitamin D levels and shorter-Term changes in plasma calcium

        Intramuscular injection of a large bolus of Vitamin D effectively increases serum 25-hydroxyVitamin D levels without evidence of metabolic abnormality. ...

        Research

        Autism and diagnostic substitution: Evidence from a study of adults with a history of developmental language disorder

        Rates of diagnosis of autism have risen since 1980, raising the question of whether some children who previously had other diagnoses are now being diagnosed... ...

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