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        Nasal delivery of a commensal Pasteurellaceae species inhibits nontypeable Haemophilus influenzae colonisation and delays onset of otitis media in mice

        We have demonstrated that a single dose of a closely related commensal can delay onset of NTHi otitis media in vivo ...

        Research

        CASSETTE-clindamycin adjunctive therapy for severe Staphylococcus aureus treatment evaluation: Study protocol for a randomised controlled trial

        This study will assess the effect of adjunctive clindamycin on patient-centred outcomes in severe, toxin-mediated S. aureus infections ...

        Research

        Evaluation of a phased pneumococcal conjugate vaccine introduction in Mongolia using enhanced pneumonia surveillance and community carriage surveys

        The enhanced surveillance system in Mongolia will facilitate assessment of PCV13 impact on pneumonia, with radiological confirmed disease as the primary outcome ...

        Research

        Mandatory vaccination and no fault vaccine injury compensation schemes: An identification of country-level policies

        Countries that mandate childhood vaccination without providing no fault compensation schemes could be seen as abrogating the social contract ...

        Research

        Assessment of on-time vaccination coverage in population subgroups: A record linkage cohort study

        On-time coverage of the 2-4-6 month schedule is only 50-60% across specific population subgroups representing a significant avoidable public health risk ...

        Research

        Nasopharyngeal carriage of Streptococcus pneumoniae: prevalence and risk factors in HIV-positive children in Tanzania

        Pneumococcal colonization of the nasopharynx is especially common in young children and is a pre-requisite for pneumococcal disease... ...

        Research

        Efficacy of the human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine in women aged 15-25 years

        We present further data on vaccine efficacy (VE) against HPV-16/18 in the total vaccinated cohort including women who may have been exposed to HPV-16/18... ...

        Research

        Is Streptococcus pyogenes resistant or susceptible to trimethoprim- sulfamethoxazole?

        Streptococcus pyogenes is commonly believed to be resistant to trimethoprim-sulfamethoxazole (SXT), resulting in reservations about using SXT for skin and... ...

        Research

        Determinants of attenuation in the envelope protein of the flavivirus Alfuy

        Murray Valley encephalitis virus (MVEV) is a mosquito-borne flavivirus endemic to Australia and Papua New Guinea. ...

        Research

        A retrospective population-based cohort study identifying target areas for prevention of acute lower respiratory infections in children

        Acute lower respiratory infections (ALRI) are a major cause of hospitalisation in young children ...

        Research

        The anti-inflammatory effects of interleukin-4 are not mediated by suppressor of cytokine signalling-1 (SOCS1)

        Authors: Woodward EA, Prêle CM, Nicholson SE, Kolesnik TB, Hart PH. Authors notes: Immunology. 2010 Sep;131(1):118-27. Epub 2010 Apr 6. Keywords: anti-inflammatory effects, interleukin-4, mediated by suppressor of cytokine signalling-1 (SOCS1) ...

        Research

        Dahlem Conference

        There is increasing evidence that the functional state of the immune system at birth is predictive of the kinetics of immune maturation in early infancy. ...

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