We report on 3 children treated with vismodegib who developed widespread growth plate fusions that persist long after cessation of therapy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• September 2017

The proposed study intends to explore parental experiences, including coping, related to their child's involvement in the early surveillance program. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• January 2014

The monkeypox virus is excreted in the feces of infected individuals. Therefore, there is an interest in using viral load detection in wastewater for sentinel early surveillance at a community level and as a complementary approach to syndromic surveillance. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Automated SMS-based reporting can facilitate sustainable, real-time, monitoring of adverse reactions and early identification of potential vaccine safety issues ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Combination vaccines containing whole-cell pertussis antigens were phased out from the Australian national immunisation programme between 1997 and 1999 and replaced by the less reactogenic acellular pertussis (aP) antigens. In a large case-control study of Australian children born during the transition period, those with allergist diagnosed IgE-mediated food allergy were less likely to have received whole-cell vaccine in early infancy than matched population controls (OR: 0.77 (95% CI, 0.62 to 0.95)). We hypothesise that a single dose of whole-cell vaccine in early infancy is protective against IgE-mediated food allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

We evaluated the frequency of moderate and severe adverse events following coadministration of seasonal influenza vaccine (SIV) versus placebo with COVID-19 vaccines among adults to support practice guidelines.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

The increasing use of assisted reproductive techniques and hormonal manipulation during pregnancy may have been associated with an apparent rise in the... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• March 2010

Raelene Nick Endersby Gottardo R NG BSc (Hons) PhD MBChB FRACP PhD Brainchild Fellow; Co-Head, Brain Tumour Research Co-Head, Brain Tumour Research raelene.endersby@telethonkids.org.au nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour ...

• 1. Telethon Kids Institute
• Projects

Physical activity is essential for children’s healthy development, yet COVID-19 physical distancing restrictions such as school closures and staying at home, playground closures, and the cancelling of organised community sport have dramatically altered children’s opportunities to be physically active. This study describes changes in levels of physical activity and screen time from February 2020 (i.e., before COVID-19 restrictions were introduced in Western Australia) to May 2020 (i.e., when COVID-19 restrictions were in place). Parents of children aged 5 to 9 years from Western Australia were eligible to participate and recruited through convenience sampling. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• March 2021

Nick Raelene Gottardo Endersby NG R MBChB FRACP PhD BSc (Hons) PhD Co-Head, Brain Tumour Research Brainchild Fellow; Co-Head, Brain Tumour Research nicholas.gottardo@telethonkids.org.au raelene.endersby@telethonkids.org.au Co-Head, Brain Tumour ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023