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        Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

        The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput. ...

        Research

        CrossTalk opposing view: Mucosal acidification does not drive early progressive lung disease in cystic fibrosis

        Whether airway mucosal acidification drives early progressive lung disease is controversial ...

        Research

        Online interventions for the mental health needs of trans and gender diverse young people

        Members of our research team have done an online survey (Trans Pathways) exploring the mental health and care pathways of gender diverse youth in Australia. ...

        Research

        Insulin Pump Therapy in Adolescents With Very Poor Glycemic Control During a 12-Month Cohort Trial

        We conclude that insulin pump therapy can be an effective tool to improve glycemic control in adolescents with long-standing treatment resistance ...

        Research

        Sustained participation in annual continuous quality improvement activities improves quality of care for Aboriginal and Torres Strait Islander children

        To determine whether participation in the CQI Audit and Best Practice for Chronic Disease programme improved care and outcomes for Indigenous children. ...

        Research

        Effects of Dietary Acute Tryptophan Depletion (ATD) on NPY Serum Levels in Healthy Adult Humans Whilst Controlling for Methionine Supply-A Pilot Study

        Acute tryptophan depletion, and therefore, diminished substrate availability for brain 5-HT synthesis did not lead to significant changes in serum neuropeptide Y concentrations over time ...

        Research

        Independent and combined effects of airway remodelling and allergy on airway responsiveness

        There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy ...

        Research

        Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

        Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells ...

        Research

        Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

        In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD. ...

        Research

        Defining relevant hypoglycemia measures in children and adolescents with type 1 diabetes

        As the choices of therapies in diabetes care multiply, it is essential to standardize the approach to measuring and recording hypoglycemia risk ...

        Research

        Determinants of a dietary pattern linked with greater metabolic risk and its tracking during adolescence

        Although growing evidence suggests that dietary patterns associated with noncommunicable disease in adulthood may develop early in life. ...

        Research

        An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

        To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins ...

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