Peanut allergy is the the most common cause of life-threatening food-induced anaphylaxis. There is currently no effective long-term treatment. There is a pressing need for definitive treatments that improve the quality of life and prevent fatalities. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• September 2020

It is well established that children’s school readiness is associated with their later academic achievement, but less is known about whether school readiness is also associated with other measures of school success, such as students’ social and emotional wellbeing. While some previous research has shown a link between early social and emotional development and student wellbeing, results are mixed and the strength of these relationships vary depending on whether data is based on child, teachers or parents ratings and which specific student wellbeing outcomes are measured. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

Preterm infants are at a high risk of developing late-onset sepsis (LOS). Lactoferrin is one of the most abundant endogenous antimicrobial proteins expressed in breast milk, stools, and blood, and a candidate for preventive intervention. Large clinical trials have recently investigated whether enteral supplementation with bovine lactoferrin reduces LOS. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

Transcription factors known to induce the epithelial-to-mesenchymal transition (EMT) (such as ZEB1/2 [zinc finger E-box binding homeobox 1/2], SNAI1/2/3, and TWIST1/2) have been undoubtedly implicated in tumorigenesis, cancer progression, metastasis, and chemoresistance in solid tumors; however, their role in normal and malignant hematopoiesis has been underappreciated for many years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020

BK polyomavirus infection in transplanted kidneys that leads to BK virus–associated nephropathy (BKVAN) is an important cause of allograft loss and has limited treatment options. Recent data suggest that BK viremia affects approximately 10% of people within the first 12 months following kidney transplantation. Among recipients with BKVAN, the overall risk of allograft loss is substantially increased, estimated to be 50% within 5 years of diagnosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

Throughout history, pandemics of viral infections such as HIV, Ebola and Influenza have disrupted health care systems, including the prevention and control of endemic diseases. Such disruption has resulted in an increased burden of endemic diseases in post-pandemic periods. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

The findings provide a method for assessing a wide range of factors that may be associated with obesity among companion dogs ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• July 2020

Findings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated by azithromycin ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Our study provides evidence that OT-82 is a promising new therapeutic strategy for a broad spectrum of high-risk pediatric acute lymphoblastic leukemia ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

The findings suggest consistency between caregivers in their reports of the difficulties experienced by children with Fetal Alcohol Spectrum Disorder ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

The aim of this study was to describe the demographic and neurocognitive profile of the first 199 individuals diagnosed with FASD in PATCHES Paediatrics clinics ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

This study examines the characteristics and outcomes of major trauma patients between transport destinations ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020