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        Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

        The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average. ...

        Research

        Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early Childhood

        Some studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown ...

        Research

        Acoustic Properties of Cries in 12-Month Old Infants at High-Risk of Autism Spectrum Disorder

        There is preliminary evidence that infant siblings of children with Autism Spectrum Disorder have an atypical pattern of crying ...

        Research

        The effects of electronic cigarette aerosol exposure on inflammation and lung function in mice

        This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function. ...

        Research

        Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

        We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception. ...

        Research

        Structure-diverse Phylomer libraries as a rich source of bioactive hits from phenotypic and target directed screens against intracellular proteins

        Phylomer libraries are being increasingly used in applications such as phenotypic screening where the numbers of peptides which can be feasibly screened is limited ...

        Research

        The NICE-GUT trial protocol: A randomised, placebo controlled trial of oral nitazoxanide for the empiric treatment of acute gastroenteritis among Australian Aboriginal children

        Diarrhoeal disease is the second leading cause of death in children under 5 years globally, killing 525 000 annually. Australian Aboriginal and Torres Strait Islander (hereafter Aboriginal) children suffer a high burden of disease. ...

        Research

        Determining the pneumococcal conjugate vaccine coverage required for indirect protection against vaccine-type pneumococcal carriage in low and middle-income countries

        We will investigate the relationship between PCV coverage and VT carriage among undervaccinated children in Asia and the Pacific ...

        Research

        Scabies and risk of skin sores in remote Australian Aboriginal communities: A self-controlled case series study

        The association between scabies and skin sores is highly significant and indicates a causal relationship ...

        Research

        Oral prednisolone in preschool children with virus-associated wheeze: A prospective, randomised, double-blind, placebo-controlled trial

        Preschool children often have episodes of virus-associated wheeze and assessing efficacy of corticosteroids for paediatric wheeze exacerbations is inconcludsive ...

        Research

        Risk and protective factors for the health of primary care-givers of children with autism spectrum disorders or ID: a narrative review

        We aimed to review original research which described factors impacting the health of primary care-givers of children with Autism or Intellectual Disability ...

        Research

        Humidified high-flow nasal cannula oxygen for bronchiolitis: Should we go with the flow?

        Current NICE 2015 guidelines for bronchiolitis state that the use of HFNC is becoming widespread without demonstration of additional efficacy. ...

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