Prenatal alcohol exposure is associated with a range of adverse offspring neurodevelopmental outcomes. Several studies suggest that PAE modifies DNA methylation in offspring cells and tissues, providing evidence for a potential mechanistic link to Fetal Alcohol Spectrum Disorder. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Our data demonstrate changes in airway responsiveness as a result of intrauterine growth restriction that could influence susceptibility to asthma development ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

This study tested the utility of optical coherence tomography-based indentation to assess mechanical properties of respiratory tissues in disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• May 2017

Alexander Anthony Dr Katherine Larcombe Kicic Landwehr A A KL BScEnv (Hons) PhD BSc (Hons) PhD BSc(Hons) Team Leader, Respiratory Environmental Health Rothwell Family Fellow; Head, Airway Epithelial Research Research Officer & PhD Anthony.Kicic@ ...

• 1. Telethon Kids Institute
• Projects

Alexander David Martyn Larcombe Martino Symons A DM MS BScEnv (Hons) PhD BSc PhD B.A. (Hons) PhD. Team Leader, Respiratory Environmental Health Head, Clinical Epigenetics Honorary Research Associate 08 6319 1672 David.Martino@telethonkids.org.au ...

• 1. Telethon Kids Institute
• Projects

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

• 1. Telethon Kids Institute
• Projects

Excessive production, secretion, and retention of abnormal mucus is a pathological feature of many obstructive airways diseases including asthma. Azithromycin is an antibiotic that also possesses immunomodulatory and mucoregulatory activities, which may contribute to the clinical effectiveness of azithromycin in asthma. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

In healthy individuals, deep inspirations (DIs) taken prior to a bronchial challenge reduce the bronchoconstrictor response, which is termed... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• October 2012

We propose that mechanical abnormalities of the airway wall acquired through disrupted fetal growth impact susceptibility to disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

The rat model demonstrates that intrauterine growth restriction leads to a more heterogeneous distribution of airway lumen calibre in adulthood ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• October 2017

A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

This study investigates the incidence of self-citation (authors citing their own work) for scholarly articles in ten journals published by the American... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011