This protocol adapted an experimental animal model of disease for sensitization to ovalbumin during the immediate post-weaning period beginning at 21 days of age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Pat Holt PG PhD, DSc, FRCPath, FRCPI, FAA Emeritus Honorary Researcher Patrick.Holt@telethonkids.org.au Emeritus Honorary Researcher Prof Holt established the Division of Cell Biology at the Institute's inception in 1990, with his research group's ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Human Immunology

Liz Tim Davis Jones EA TW MBBS FRACP PhD MBBS DCH FRACP MD Head, Chronic & Severe Diseases Research Focus Area; Clinical Lead, Diabetes and Obesity Research Co-head, Diabetes and Obesity Research Head, Chronic & Severe Diseases Research Focus Area; ...

• 1. Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Diabetes, Metabolism and Clinical Sciences
• Diabetes and Obesity Research
• Expired Projects

Obstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography (PSG) remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• August 2023

The EU LifeCycle Project was launched in 2017 to combine, harmonise, and analyse data from more than 250,000 participants across Europe and Australia, involving cohorts participating in the EU-funded LifeCycle Project. The purpose of this cohort description is to provide a detailed overview over the major measures within mental health domains that are available in 17 European and Australian cohorts participating in the LifeCycle Project. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

This study is looking for the causes of type 1 diabetes, so that we can find ways to prevent it. Type 1 diabetes in children is twice as common as it was 20 years ago. This is because of the environment that we live in has changed and this has made ...

• 1. Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Diabetes, Metabolism and Clinical Sciences
• Diabetes and Obesity Research

We are living in a time of unprecedented risk for noncommunicable diseases (NCDs), such as obesity, cardiovascular disease, diabetes, cancer... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Intra-breath forced oscillation technique can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

Early-life obstructive sleep apnoea (OSA) predictors are unavailable for young adults. This study identifies early-life factors predisposing young adults to OSA. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

A targeted program would have the potential to prevent one-quarter of the cases of being vulnerable on two or more AEDC domains at age five ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Parental pre-pregnancy body mass index and rapid early-life weight gain predispose offspring to obesity in adulthood ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• March 2016

These observations suggest factors in the modern environment promote pancreatic islet autoimmunity and destruction of insulin-producing beta cells. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013