Laboratory models provide an important tool in helping to understand the cellular and molecular drivers of respiratory disease. Many animal models exist that model the neonatal outcomes of preterm birth. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

Nasal epithelial cells from very preterm infants have a functional defect in their ability to repair beyond the first year of life, and failed repair may be associated with antenatal steroid exposure. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• June 2021

Lung function trajectories are impaired in survivors of very preterm birth ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• May 2018

Background: We assessed the effect of posture on ventilation distribution and the impact on associations with structural lung disease. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

The authors assessed the impact of including preschool‐aged children with a history of preterm birth, early life wheeze, asthma diagnoses and/or recent respiratory symptoms in healthy reference ranges for respiratory impedance using the forced oscillation technique (FOT). ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018

Neisseria meningitidis serogroup B is a major cause of invasive meningococcal disease, but a broadly protective vaccine is not currently licensed. A bivalent... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

We describe here the effects of treatment with interferon-α2b in a cohort of confirmed COVID-19 cases in Wuhan, China ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Vaccination to prevent infectious disease is one of the most successful public health interventions ever developed. And yet, variability in individual vaccine effectiveness suggests that a better mechanistic understanding of vaccine-induced immune responses could improve vaccine design and efficacy. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Early life is marked by distinct and rapidly evolving immunity and increased susceptibility to infection. The vulnerability of the newborn reflects development of a complex immune system in the face of rapidly changing demands during the transition to extra-uterine life. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021

Cystic fibrosis (CF) is the most common chronic, life-shortening genetic condition affecting young Australians. There is no cure but researchers are working to prevent the onset of lung disease. ...

• Telethon Kids Institute
• Our research
• Research Topics

Distinct differences in microbiome compositions were found in both oropharyngeal and fecal samples of Australian Chinese and Chinese-born Chinese children ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Jonathan Rosemary Carapetis AM Wyber JR R AM MBBS FRACP FAFPHM PhD FAHMS MBChB MPH FRACGP PhD Executive Director; Head, Strep A Translation; Co-Founder of REACH Senior Research Fellow 08 6319 1000 contact@telethonkids.org.au Institute Director; Head ...

• Telethon Kids Institute
• Projects