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        37-48 of 345 results for 'south australia'

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        Global economic costs due to vivax malaria and the potential impact of its radical cure: A modelling study

        An estimated 14 million cases of Plasmodium vivax malaria were reported from Asia, Central and South America, and the Horn of Africa. The clinical burden of vivax malaria is largely driven by its ability to form dormant liver stages (hypnozoites) that can reactivate to cause recurrent episodes of malaria. Elimination of both the blood and liver stages of the parasites ("radical cure") is required to achieve a sustained clinical response and prevent ongoing transmission of the parasite. ...

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        RaScALL: Rapid (Ra) screening (Sc) of RNA-seq data for prognostically significant genomic alterations in acute lymphoblastic leukaemia (ALL)

        RNA-sequencing (RNA-seq) efforts in acute lymphoblastic leukaemia have identified numerous prognostically significant genomic alterations which can guide diagnostic risk stratification and treatment choices when detected early. ...

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        Evaluation of the Learning+ Pilot Program

        Yasmin Adrienne Harman-Smith Gregory YHS adrienne.gregory@telethonkids.org.au BA, BHlthSc(Hons), PhD BSocSci, MPhil Head, Early Years Systems Evidence; Head, Tenders Support Unit Project Officer Yasmin.harman-smith@telethonkids.org.au ...

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        Associations Between the Early Development Instrument at Age 5, and Reading and Numeracy Skills at Ages 8, 10 and 12: a Prospective Linked Data Study

        The objective of this paper is to determine how well the EDI predicts a child's later literacy and numeracy outcomes as assessed by the National Assessment... ...

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        Determinants of lung function development from birth to age 5 years: an interrupted time series analysis of a South African birth cohort

        Early life is a key period that determines long-term health. Lung development in childhood predicts lung function attained in adulthood and morbidity and mortality across the life course. We aimed to assess the effect of early-life lower respiratory tract infection (LRTI) and associated risk factors on lung development from birth to school age in a South African birth cohort. ...

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        Review of Universal Access Funded Aboriginal Children with Hearing Impairment Support Program

        Ellen Adrienne Yasmin Harvey Gregory Harman-Smith EH adrienne.gregory@telethonkids.org.au YHS BSocWk(Hons) BSocSci, MPhil BA, BHlthSc(Hons), PhD Senior Project Coordinator Project Officer Head, Early Years Systems Evidence; Head, Tenders Support ...

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        DraculR: A Web-Based Application for In Silico Haemolysis Detection in High-Throughput microRNA Sequencing Data

        The search for novel microRNA (miRNA) biomarkers in plasma is hampered by haemolysis, the lysis and subsequent release of red blood cell contents, including miRNAs, into surrounding fluid. The biomarker potential of miRNAs comes in part from their multicompartment origin and the long-lived nature of miRNA transcripts in plasma, giving researchers a functional window for tissues that are otherwise difficult or disadvantageous to sample. ...

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        Understanding valvular heart disease in the dental setting

        Limited evidence is available regarding dentists' knowledge and interpretation of infective endocarditis (IE) prophylaxis guidelines. The aim of this study was to determine understanding and management of rheumatic and non-rheumatic valvular heart disease (VHD) in the dental setting in Western Australia (WA). ...

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        3DFAACTS-SNP: using regulatory T cell-specific epigenomics data to uncover candidate mechanisms of type 1 diabetes (T1D) risk

        Genome-wide association studies (GWAS) have enabled the discovery of single nucleotide polymorphisms (SNPs) that are significantly associated with many autoimmune diseases including type 1 diabetes (T1D). However, many of the identified variants lie in non-coding regions, limiting the identification of mechanisms that contribute to autoimmune disease progression. ...

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        Mapping the landscape of chromatin dynamics during naïve CD4+ T-cell activation

        T-cell activation induces context-specific gene expression programs that promote energy generation and biosynthesis, progression through the cell cycle and ultimately cell differentiation. The aim of this study was to apply the omni ATAC-seq method to characterize the landscape of chromatin changes induced by T-cell activation in mature naïve CD4+ T-cells. ...

        Research

        Childhood vaccination coverage in Australia: an equity perspective

        This study describes trends in social inequities in first dose measles-mumps-rubella (MMR1) vaccination coverage in Western Australia (WA) and New South Wales (NSW). ...

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        Incidence of Stroke in the Aboriginal and Non-Aboriginal Populations of Australia: A Data Linkage Study

        Most estimates of stroke incidence among Aboriginal and Torres Strait Islander (hereinafter Aboriginal) Australians are confined to single regions and include small sample sizes. We aimed to measure and compare stroke incidence in Aboriginal and non-Aboriginal residents across central and western Australia. ...

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