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        Subgroups of Temperament Associated with Social-Emotional Difficulties in Infants with Early Signs of Autism

        Links between temperament and social-emotional difficulties are well-established in normative child development but remain poorly characterized in autism. We sought to characterize distinct temperament subgroups and their associations with concurrent internalizing and externalizing symptoms in a sample of 103 infants showing early signs of autism. ...

        Research

        Airway management in neonates and infants: Recommendations according to the ESAIC/BJA guidelines

        Securing an airway enables the oxygenation and ventilation of the lungs and is a potentially life-saving medical procedure. Adverse and critical events are common during airway management, particularly in neonates and infants. The multifactorial reasons for this include patient-dependent, user-dependent and also external factors. ...

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        Hypothesis-driven genome-wide association studies provide novel insights into genetics of reading disabilities

        Reading Disability is often characterized by difficulties in the phonology of the language. While the molecular mechanisms underlying it are largely undetermined, loci are being revealed by genome-wide association studies. ...

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        Harmonized Phenotypes for Anxiety, Depression, and Attention-Deficit Hyperactivity Disorder (ADHD)

        In multi-cohort consortia, the problem often arises that a phenotype is measured using different questionnaires. This study aimed to harmonize scores based on the Child Behaviour Check List (CBCL) and the Strength and Difficulties Questionnaire (SDQ) for anxiety/depression and ADHD. ...

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        The effect of oxytocin nasal spray on social interaction in young children with autism: a randomized clinical trial

        Early supports to enhance social development in children with autism are widely promoted. While oxytocin has a crucial role in mammalian social development, its potential role as a medication to enhance social development in humans remains unclear. ...

        Research

        A national harmonised data collection network for neurodevelopmental disorders: A transdiagnostic assessment protocol for neurodevelopment, mental health, functioning and well-being

        Children with neurodevelopmental disorders share common phenotypes, support needs and comorbidities. Such overlap suggests the value of transdiagnostic assessment pathways that contribute to knowledge about research and clinical needs of these children and their families. ...

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        The effects of JASPER intervention for children with autism spectrum disorder: A systematic review

        Naturalistic developmental behavioural interventions are promising approaches for young children with, or suspected of having, autism spectrum disorder. Joint attention, symbolic play, engagement and regulation intervention (JASPER) is a well-researched naturalistic developmental behavioural intervention but, to date, no reviews have specifically evaluated its effects. ...

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        CNTNAP2 variants affect early language development in the general population

        We tested the hypothesis that these CNTNAP2 variants affect communicative behavior, measured at 2 years of age in a large epidemiological sample... ...

        Research

        Inner speech impairment in children with autism is associated with greater nonverbal than verbal skills

        We present a new analysis of Whitehouse, Maybery, and Durkin's (2006, Experiment 3) data on inner speech in children with autism (CWA). ...

        Research

        Implementation of the National Guideline for the Assessment and Diagnosis of ASD in Australia – Health Sector Capacity Building

        Andrew Whitehouse Watch and listen to Andrew AJ PhD Angela Wright Bennett Professor of Autism Research at Telethon Kids Institute; Director, CliniKids Andrew.Whitehouse@telethonkids.org.au Angela Wright Bennett Professor of Autism Research at ...

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        Utilising Behavioural and Sensory Profiles and Associated Perinatal Factors to Identify Meaningful Subgroups in Autism Spectrum Disorder

        The heterogeneity of autism spectrum disorder clinically and aetiologically hinders intervention matching and prediction of outcomes. This study investigated if the behavioural, sensory, and perinatal factor profiles of autistic children could be used to identify distinct subgroups. Participants on the autism spectrum aged 2 to 17 years and their families were sourced via the Australian Autism Biobank. ...

        Research

        Anesthetic Exposure During Childhood and Neurodevelopmental Outcomes: A Systematic Review and Meta-analysis

        Clinical studies of neurodevelopmental outcomes after anesthetic exposure have evaluated a range of outcomes with mixed results. ...

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