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        COVID-19

        Here’s what we know so far about the impact of COVID-19 on children. ...

        Research

        A Rationale for Change: An Increase in Invasive Pneumococcal Disease in Fully Vaccinated Children

        A review of cases informed a change from a "3 + 0" infant schedule to a "2 + 1" schedule ...

        Research

        Birth outcomes in Aboriginal mother–infant pairs from the Northern Territory, Australia, who received 23-valent polysaccharide pneumococcal vaccination during pregnancy

        We found a numerically higher rate of preterm births among women who received 23vPPV in pregnancy compared to unvaccinated pregnant women ...

        Research

        Atlas of group A streptococcal vaccine candidates compiled using large-scale comparative genomics

        We identified the existence of more than 290 clinically associated genomic phylogroups across 22 countries, highlighting challenges in designing vaccines of global utility ...

        Research

        No detectable effects of acute tryptophan depletion on short-term immune system cytokine levels in healthy adults

        The acute tryptophan depletion condition did not result in significant changes to cytokine concentrations for the entire study sample ...

        Research

        High risk of early sub-therapeutic penicillin concentrations after intramuscular benzathine penicillin G injections in Ethiopian children and adults with rheumatic heart disease

        Intramuscular benzathine penicillin G (BPG) injections are a cornerstone of secondary prophylaxis to prevent acute rheumatic fever (ARF) and rheumatic heart disease (RHD). Uncertainties regarding inter-ethnic and preparation variability, and target exposure profiles of BPG injection are key knowledge gaps for RHD control. ...

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        Blueprint for the House Dust Mite

        The completeness of the coverage of a genome assembly is a critical starting point for all genomic projects so considerable attention is given to the sequencing metrics, which showed high indicators of success. ...

        Research

        Barriers to Parent–Child Book Reading in Early Childhood

        Parent–child book reading interventions alone are unlikely to meet needs of children and families for whom the absence of reading is psychosocial risk factor ...

        Research

        An atlas of human long non-coding RNAs with accurate 5′ ends

        Combining these findings with conservation data, we identify 19,175 potentially functional lncRNAs in the human genome. ...

        Research

        Prevalence of microcephaly in an Australian population-based birth defects register, 1980-2015

        We identified a high proportion of cases without known cause, highlighting the need for clinicians to carefully investigate all possibilities, including emerging infections. ...

        Research

        Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages

        A comprehensive in depth gene expression/regulation profile in Mycobacterium tuberculosis-infected macrophages ...

        Research

        No relationship between autistic traits and salivary testosterone concentrations in men from the general population

        The current data add to the increasing evidence for the lack of relationship between autistic traits and postnatal levels of testosterone in men ...

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