Invasive fungal disease (IFD) remains a challenging complication of treatment for paediatric acute leukaemia. Consensus fungal treatment guidelines recommend withholding chemotherapy to facilitate immune recovery in this setting, yet prolonged delays in leukaemia therapy increase risk of relapse. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• June 2022

Modern precision sequencing techniques have established humans as a holobiont that live in symbiosis with the microbiome. Microbes play an active role throughout the life of a human ranging from metabolism and immunity to disease tolerance. Hence, it is of utmost significance to study the eukaryotic host in conjunction with the microbial antigens to obtain a complete picture of the host-microbiome crosstalk.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• April 2024

This study provides evidence to support annual inactivated influenza vaccine administration to children following allogeneic haematopoietic stem cell transplant ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

We report data from the interim analysis of the ongoing VIVIANE study, the aim of which is to assess the efficacy, safety, and immunogenicity of the HPV... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• September 2014

This Australia-wide study examines whether maternal intake of folate and vitamins B6 and B12 during pregnancy is associated with development of brain tumors... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• June 2014

We are living in a time of unprecedented risk for noncommunicable diseases (NCDs), such as obesity, cardiovascular disease, diabetes, cancer... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Our findings provide some evidence of an association between maternal smoking during pregnancy and Neuroblastoma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• December 2019

This paper discusses the risk of developing malignant mesothelioma more than 40 years after the first exposure to asbestos. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• May 2014

Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

The discovery of CRISPR-Cas9 and its widespread use has revolutionised and propelled research in biological sciences. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

The transcriptome represents the entire set of RNA transcripts expressed in a cell, reflecting both the underlying genetic and epigenetic landscape and environmental influences, providing a comprehensive view of functional cellular states at any given time. Recent technological advances now enable the study of the transcriptome at the resolution of individual cells, providing exciting opportunities to characterise cellular and molecular events that underpin immune-medicated diseases. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020