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        Independent and combined effects of airway remodelling and allergy on airway responsiveness

        There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy ...

        Research

        Group A Streptococcus M1T1 Intracellular Infection of Primary Tonsil Epithelial Cells Dampens Levels of Secreted IL-8 Through the Action of SpyCEP

        Our results suggest that intracellular infection with the pathogenic GAS M1T1 clone induces a strong pro-inflammatory response in primary tonsil epithelial cells ...

        Research

        Online interventions for the mental health needs of trans and gender diverse young people

        Members of our research team have done an online survey (Trans Pathways) exploring the mental health and care pathways of gender diverse youth in Australia. ...

        Research

        Clinical significance of circulating microRNAs as markers in detecting and predicting congenital heart defects in children

        In this study, we aimed to investigate the usefulness of miRNAs as biomarkers in diagnosing and predicting children with congenital heart defects (CHD), particularly in the context of multiple subtypes of CHD. ...

        Research

        Determinants of a dietary pattern linked with greater metabolic risk and its tracking during adolescence

        Although growing evidence suggests that dietary patterns associated with noncommunicable disease in adulthood may develop early in life. ...

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        The NICE-GUT trial protocol: A randomised, placebo controlled trial of oral nitazoxanide for the empiric treatment of acute gastroenteritis among Australian Aboriginal children

        Diarrhoeal disease is the second leading cause of death in children under 5 years globally, killing 525 000 annually. Australian Aboriginal and Torres Strait Islander (hereafter Aboriginal) children suffer a high burden of disease. ...

        Research

        Investigating facial phenotype in autism spectrum conditions: The importance of a hypothesis driven approach

        The identification of differences in the facial phenotype of individuals with ASC may contribute to efforts to promote early identification of the condition and help elucidate etiological pathways. ...

        Research

        Relationship between early motor milestones and severity of restricted and repetitive behaviors in children and adolescents with autism spectrum disorder

        This study provides the first evidence for the association between restricted and repetitive behaviors and age of attainment of early motor milestones. ...

        Research

        Are scabies and impetigo “normalised”? A cross-sectional comparative study of hospitalised children in northern Australia assessing clinical recognition

        Scabies and impetigo infections are under-recognised and hence under-treated by clinicians ...

        Research

        Repeated vaccination does not appear to impact upon influenza vaccine effectiveness against hospitalization with confirmed influenza

        These findings reinforce current recommendations for annual influenza vaccination, particularly those at greatest risk of influenza disease. ...

        Research

        Burden of cardiovascular diseases in the Eastern Mediterranean Region, 1990-2015: findings from the Global Burden of Disease 2015 study

        The age-standardized disability-adjusted life years rates in the Eastern Mediterranean Region are considerably higher than the global average. ...

        Research

        Latent Class Analysis of Neurodevelopmental Deficit After Exposure to Anesthesia in Early Childhood

        Some studies suggest an association between early exposure to anesthesia, surgery and long term developmental deficit, clinical phenotype of children is unknown ...

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