Studies linking early life exposure to air pollution and subsequent impaired lung health have focused on chronic, low-level exposures in urban settings. We aimed to determine whether in utero exposure to an acute, high-intensity air pollution episode impaired lung function 7-years later. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

Spacer device was not associated with clinically important differences in lung function following bronchodilator inhalation in children with asthma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

We describe contemporary antifungal use in neonates, with point-prevalence survey data from the National Antimicrobial Prescribing Survey across Australian hospitals from 2014 to 2018. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

Infants aged <6 months are vulnerable to severe influenza disease and no vaccine is approved for use in this age group. We aimed to describe the epidemiology, risk factors associated with severe outcomes and management of influenza in Australian infants aged <6 months. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Scedosporium spp. are the second most prevalent filamentous fungi after Aspergillus spp. recovered from cystic fibrosis (CF) patients in various regions of the world. Although invasive infection is uncommon prior to lung transplantation, fungal colonization may be a risk factor for invasive disease with attendant high mortality post-transplantation. Abundant in the environment, Scedosporium aurantiacum has emerged as an important fungal pathogen in a range of clinical settings. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Diesel engine exhaust exposures were higher in underground miners and had a negative association with their lung function over a single 12-h shift ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

Routine MPS screening for Maturity-onset diabetes of the young in the pediatric population with diabetes could reduce health system costs and improve patient QoL ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

CGM with remote monitoring was found to improve multiple measures of quality of life, reduce family stress, and improve parental sleep ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

This study provides evidence for a possible plateauing in the incidence of childhood T1D in Western Australia, following a peak in 2003 ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• June 2018

Infant lung function (ILF) testing may provide useful information about lung growth and susceptibility to respiratory disease. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• December 2013

Alexander Larcombe A BScEnv (Hons) PhD Team Leader, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at the Telethon Institute in 2005 and is now a Senior Research ...

• Telethon Kids Institute
• Projects

Receiving vaccines at or close to their due date (vaccination timeliness) is a now key measure of program performance. However, studies comprehensively examining predictors of delayed infant vaccination are lacking. We aimed to identify predictors of short and longer-term delays in diphtheria-tetanus-pertussis (DTP) vaccination by dose number and ethnicity. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• August 2020