Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

Our approach to hematopoietic progenitor cells mobilization resulted in highly effective HPC harvest in children and adolescents with high-risk cancers ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

Although neurocognitive, psychological and behavioural problems were noted for some patients during medical review, only 20% of patients were formally assessed. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

Non-Aspergillus molds and non-albicans Candida contributed substantially to pediatric invasive fungal infection in our study ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• April 2019

There is a high incidence of vaccine-preventable morbidity post-allogeneic haematopoietic stem cell transplantation in West Australian children ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

The aim of this project was to identify the top 10 priorities for childhood chronic conditions and disability (CCD) research from the perspectives of children and young people with lived experience, their parents and caregivers and the professionals who work with them. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

Invasive fungal disease (IFD) remains a common and serious complication in children treated for leukaemia. Antifungal prescription in children with leukaemia presents unique challenges, particularly due to variation in IFD risk between and within leukaemia treatment protocols, drug toxicities and interactions between antifungals and chemotherapeutic agents. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Transcription of the human mitochondrial genome and correct processing of the two long polycistronic transcripts are crucial for oxidative phosphorylation. According to the tRNA punctuation model, nucleolytic processing of these large precursor transcripts occurs mainly through the excision of the tRNAs that flank most rRNAs and mRNAs. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• November 2021

There is insufficient evidence available to determine whether these organisms are pathogens, commensals or contribute indirectly to the pathogenesis of OM ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

This study utilized in vitro, in vivo and clinical data to evaluate the palatability of a novel midazolam chocolate tablet. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Sarcomeric gene mutations are associated with the development of hypertrophic cardiomyopathy (HCM). Current drug therapeutics for HCM patients are effective in relieving symptoms, but do not prevent or reverse disease progression. Moreover, due to heterogeneity in the clinical manifestations of the disease, patients experience variable outcomes in response to therapeutics. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

Mitochondria rely on coordinated expression of their own mitochondrial DNA (mtDNA) with that of the nuclear genome for their biogenesis. The bacterial ancestry of mitochondria has given rise to unique and idiosyncratic features of the mtDNA and its expression machinery that can be specific to different organisms. In animals, the mitochondrial protein synthesis machinery has acquired many new components and mechanisms over evolution. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024