Amphotericin B provides improved therapy for visceral leishmaniasis (VL) caused by Leishmania donovani ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

Susan Prescott SL MBBS BMedSci PhD FRACP Honorary Research Fellow susan.prescott@telethonkids.org.au Honorary Research Fellow Susan Prescott is a Professor of Paediatrics in the School of Medicine at the University of Western Australia. She is a ...

• 1. Telethon Kids Institute
• Projects

The heart failure epidemic is growing and its prevention, in order to reduce associated hospital readmission rates and its clinical and economic burden, is a key issue in modern cardiovascular medicine. The present consensus document aims to provide practical evidence-based information to support the implementation of effective preventive measures. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Vitamin D may be responsible for reducing the development and severity of autoimmune and allergic diseases. Topically applied 1,25-dihydroxyvitamin D(3) (1,25(O ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

Topical creams containing the active form of vitamin D (1,25-dihydroxyvitamin D3; 1,25(OH)2D3) or analogues of this compound are currently used with some succes ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• July 2010

The aim of this study was to identify sex-specific differences in the metabolome and its relation to components of the metabolic syndrome in a young adult population ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• March 2017

The prevalence of vitamin D deficiency is increasing and has been linked to obstructive lung diseases including asthma and chronic obstructive pulmonary disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• February 2011

The prevalence of scar formation following Bacille Calmette-Guérin (BCG) vaccination varies globally. The beneficial off-target effects of BCG are proposed to be stronger amongst children who develop a BCG scar. Within an international randomised trial ('BCG vaccination to reduce the impact of coronavirus disease 2019 (COVID-19) in healthcare workers'; BRACE Trial), this nested prospective cohort study assessed the prevalence of and factors influencing scar formation, as well as participant perception of BCG scarring 12 months following vaccination. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

Amidst the evolving COVID-19 pandemic, understanding the transmission dynamics of the SARS-CoV-2 virus is key to providing peace of mind for the community and informing policy-making decisions. While available data suggest that school-aged children are not significant spreaders of SARS-CoV-2, the possibility of transmission in schools remains an ongoing concern, especially among an aging teaching workforce. Even in low-prevalence settings, communities must balance the potential risk of transmission with the need for students' ongoing education. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• February 2021

Direct UV irradiation of dendritic cells and Langerhans cells reduces their Ag presenting ability. However, the effects of UV on CD11c(+) cells located... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• December 2010

The active form of vitamin D has an important role in calcium metabolism and in bone mineralisation, but the evidence for other health outcomes is mixed,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014