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        481-492 of 785 results for 'asthma'

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        Cystic fibrosis clinical isolates of aspergillus fumigatus induce similar muco-inflammatory responses in primary airway epithelial cells

        Aspergillus is increasingly associated with lung inflammation and mucus plugging in early cystic fibrosis disease during which conidia burden is low and strains appear to be highly diverse. It is unknown whether clinical Aspergillus strains vary in their capacity to induce epithelial inflammation and mucus production. ...

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        Investigating the Implications of CFTR Exon Skipping Using a Cftr Exon 9 Deleted Mouse Model

        Severity and disease progression in people with Cystic Fibrosis is typically dependent on their genotype. One potential therapeutic strategy for people with specific mutations is exon skipping with antisense oligonucleotides. CFTR exon 9 is an in-frame exon and hence the exclusion of this exon would excise only 31 amino acids but not alter the reading frame of the remaining mRNA. ...

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        Standardization of Spirometry 2019 Update. An Official American Thoracic Society and European Respiratory Society Technical Statement

        Standards and consensus recommendations are presented for manufacturers, clinicians, operators, and researchers ...

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        ERS technical standard on bronchial challenge testing: General considerations and performance of methacholine challenge tests

        This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. ...

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        Respiratory function in healthy Emirati children using forced oscillations

        Forced oscillation technique measurements were feasible in Emirati school-children. New forced oscillation technique reference equation in Emirati children were derived. ...

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        Immune-Microbiota Interactions: Dysbiosis as a Global Health Issue

        The implications of the microbiome extend to virtually every branch of medicine, biopsychosocial and environmental sciences ...

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        The all-age spirometry reference ranges reflect contemporary Australasian spirometry

        Advances in statistical modelling have allowed the creation of smoothly changing spirometry reference ranges that apply across a wide age range and better... ...

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        Molecular characterization of Der p 10: A diagnostic marker for broad sensitization in house dust mite allergy

        Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin ...

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        Air travel and the risks of hypoxia in children

        In infants and children with chronic respiratory disease, hypoxia is a potential risk of aircraft travel. ...

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        Age- and height-based prediction bias in spirometry reference equations

        Prediction bias in spirometry reference equations can arise from combining equations for different age groups,... ...

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        Influence of secular trends and sample size on reference equations for lung function tests

        The aim of our study was to determine the contribution of secular trends and sample size to lung function reference equations, and establish the number... ...

        Research

        Histone modifications and their role in epigenetics of atopy and allergic diseases

        This review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases ...

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