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        ANRIL Promoter DNA Methylation: A Perinatal Marker for Later Adiposity

        Experimental studies show a substantial contribution of early life environment to obesity risk through epigenetic processes. ...

        Research

        An in silico pipeline to filter the Toxoplasma gondii proteome for proteins that could traffic to the host cell nucleus and influence host cell epigenetic regulation

        To identify genes with putative epigenetic functions, we developed an in silico pipeline to interrogate the T. gondii proteome of 8313 proteins ...

        Research

        Risk and protective factors for the health of primary care-givers of children with autism spectrum disorders or ID: a narrative review

        We aimed to review original research which described factors impacting the health of primary care-givers of children with Autism or Intellectual Disability ...

        Research

        Humidified high-flow nasal cannula oxygen for bronchiolitis: Should we go with the flow?

        Current NICE 2015 guidelines for bronchiolitis state that the use of HFNC is becoming widespread without demonstration of additional efficacy. ...

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        Linking FANTOM5 CAGE peaks to annotations with CAGEscan

        Here, we present the production and quality control of CAGEscan libraries from 56 FANTOM5 RNA sources ...

        Research

        The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults

        We report the case of a 45-year-old woman who was diagnosed with a NOS based on immunohistochemical analysis of the patient's tumor at diagnosis. ...

        Research

        Reticulon-1 and reduced migration toward chemoattractants by macrophages differentiated from the bone marrow of ultraviolet-irradiated and ultraviolet-chimeric mice

        By using an anti-reticulon-1 Ab, a role for reticulon-1 in macrophage migration toward both CSF-1 and CCL2 was confirmed. ...

        Research

        Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children

        The present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric acute respiratory infection (ARI). ...

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        Epigenome-wide analysis links SMAD3 methylation at birth to asthma in children of asthmatic mothers

        We sought to assess whether the trajectory to asthma begins already at birth and whether epigenetic mechanisms, contribute to asthma inception. ...

        Research

        Adversity and resilience amongst resettling Western Australian paediatric refugees

        Refugee children have complex backgrounds with exposure to multiple traumatic events. ...

        Research

        Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

        The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput. ...

        Research

        Longitudinal study of language and speech of twins at 4 and 6 years: Twinning effects decrease, zygosity effects disappear, and heritability increases

        This study investigates the heritability of language, speech, and nonverbal cognitive development of twins at 4 and 6 years of age. ...

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