A standardised framework for selecting outcomes for evaluation in trials has been proposed by the Core Outcome Measures in Effectiveness Trials working group. However, this method does not specify how to ensure that the outcomes that are selected are causally related to the disease and the health intervention being studied. Causal network diagrams may help researchers identify outcomes that are both clinically meaningful and likely to be causally dependent on the intervention, and endpoints that are, in turn, causally dependent on those outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• October 2021

We present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

Significant influenza-associated morbidity was observed in 2017 in Australia. Vaccine coverage and antiviral use was inadequate. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• March 2019

In response to DNA damaging chemotherapy, targeting MK2 in p53-mutated cells produces a phenotype that is distinct from the p53-deficient phenotype ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

Vaccination is the most effective strategy for preventing influenza infection in pregnancy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

In children, we found no relationship between Prn status and markers of severe pertussis ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Our objective was to describe the epidemiology, clinical features, health care resource use, treatment and outcomes of multidrug-resistant tuberculosis... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014

We performed a 2-week prospective survey of formal ID physician activities related to direct inpatient care, encompassing 53 hospitals throughout Australia,... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• October 2014

Using a dataset of Australian children, we have the opportunity to not only investigate the transfer of educational resources across 3 generations in Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• March 2018

Understanding variations in risk profiles among persistently non-attending children will inform the development of absence interventions. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

There are strong socioeconomic and psychosocial gradients in both current smoking and smoking cessation. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

We examined the relationship between the onset and pattern of childhood mental health disorders and subsequent current smoking status at age 17 years. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012