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        The mechanism or mechanisms driving atopic asthma initiation: The infant respiratory microbiome moves to center stage

        Although debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment... ...

        Research

        Childhood behavior problems and age at first sexual intercourse: A prospective birth cohort study

        Early first sexual intercourse (FSI) is a risk factor for unplanned abstract teenage pregnancy, sexually transmitted infection, and adverse social, emotional... ...

        Research

        High Nasopharyngeal Carriage of Non-Vaccine Serotypes in Western Australian Aboriginal People Following 10 Years of Pneumococcal Conjugate Vaccination

        Invasive pneumococcal disease (IPD) continues to occur at high rates among Australian Aboriginal people. ...

        Research

        Prevalence of and risk factors for human rhinovirus infection in healthy aboriginal and non-aboriginal western australian children

        Human rhinovirus (HRV) species C (HRV-C) have been associated with frequent and severe acute lower respiratory infections and asthma in hospitalized children. ...

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        Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled Trial

        We conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7) given in... ...

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        Immunization of newborns with bacterial conjugate vaccines

        Bacterial conjugate vaccines are based on the principle of coupling immunogenic bacterial capsular polysaccharides to a carrier protein to facilitate the... ...

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        Polymorphisms in key innate immune genes and their effects on measles vaccine responses and vaccine failure in children from Mozambique

        Despite an effective vaccine, measles remains a major health problem globally, particularly in developing countries. More than 30% of children show primary... ...

        Research

        Comparison of three methods for the recovery of skin pathogens from impetigo swabs collected in a remote community of Northern Territory, Australia

        Immediate plating of impetigo swabs is the gold standard for bacterial recovery but is rarely feasible in remote regions. ...

        Research

        Reduction in disparity for pneumonia hospitalisations between Australian indigenous and non-Indigenous children

        In the 1990s pneumonia hospitalisation rates in Western Australia (WA) were 13 times higher in Indigenous children than in non-Indigenous children... ...

        Research

        IgG Responses to Pneumococcal and Haemophilus Influenzae Protein Antigens Are Not Impaired in Children with a History of Recurrent Acute Otitis Media

        Vaccines including conserved antigens from Streptococcus pneumoniae & nontypeable Haemophilus influenzae have the potential to reduce of otitis media. ...

        Research

        Changes in thymic regulatory T-cell maturation from birth to puberty: Differences in atopic children

        We report vaccine efficacy against CIN3+ and adenocarcinoma in situ (AIS) in the end-of-study analysis of PATRICIA (PApilloma TRIal against Cancer In young... ...

        Research

        Acute Rheumatic Fever and Chronic Rheumatic Disease

        This chapter describes the epidemiology, pathogenesis, clinical manifestations, diagnostic criteria, and management principles of acute rheumatic fever. ...

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