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        A randomized comparison of three prandial insulin dosing algorithms for children and adolescents with Type 1 diabetes

        The Pankowska Equation resulted in reduced postprandial hyperglycaemia at the expense of an increase in hypoglycaemia ...

        Research

        Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early life

        Intra-breath forced oscillation technique can identify healthy infants at risk of developing LRTI, wheezing or severe illness in the first year of life ...

        Research

        Unexpected Management Behaviors in Adolescents With Type 1 Diabetes Using Sensor-Augmented Pump Therapy

        Constant exposure to real-time data can lead to unsafe management responses in adolescents with the behavior influenced by trust or mistrust in the system ...

        Research

        Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort study

        There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments. ...

        Research

        Diagnosis and analysis of unexplained cases of childhood encephalitis in Australia using metatranscriptomic sequencing

        Encephalitis is most often caused by a variety of infectious agents identified through diagnostic tests utilizing cerebrospinal fluid. We investigated the clinical characteristics and potential aetiological agents of unexplained encephalitis through metagenomic sequencing of residual clinical samples from multiple tissue types and independent clinical review. ...

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        Do rapid diagnostic methods improve antibiotic prescribing in paediatric bacteraemia?

        Rapid blood culture pathogen identification facilitated by matrix-assisted laser desorption ionisation time-of-flight and GeneXpert has the potential to improve antibiotic prescribing. This study investigates the impact of these rapid diagnostics on the timeliness of effective and optimal antibiotic prescribing in paediatric patients with bacteraemia. ...

        Research

        Official ERS technical standards: Global Lung Function Initiative reference values for the carbon monoxide transfer factor for Caucasians

        This is the largest collection of normative T LCO data, and the first global reference values available for T LCO. ...

        Research

        Investigating the relationship between environmental factors and respiratory health outcomes in school children using the forced oscillation technique

        The significance of both indoor and outdoor sources of air pollution and effect modifiers such as green space and heating require further investigation ...

        Research

        Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: An illustrative case series

        We describe a series of 6 cases where adoption of a low carbohydrate diet in children impacted growth and cardiovascular risk factors with potential long-term sequelae. ...

        Research

        Reproducibility of the plasma glucose response to moderate-intensity exercise in adolescents with Type 1 diabetes

        The plasma glucose response to moderate-intensity exercise can be reproducible in adolescents with Type 1 diabetes ...

        Research

        Prospective characterisation of SARS-CoV-2 infections among children presenting to tertiary paediatric hospitals across Australia in 2020: A national cohort study

        To present Australia-wide data on paediatric COVID-19 and multisystem inflammatory syndromes to inform health service provision and vaccination prioritisation. Design Prospective, multicentre cohort study. Setting Eight tertiary paediatric hospitals across six Australian states and territories in an established research surveillance network - Paediatric Active Enhanced Disease (PAEDS). ...

        Research

        Consensus guidelines for the diagnosis and management of cryptococcosis and rare yeast infections in the haematology/oncology setting, 2021

        Cryptococcosis caused by the Cryptococcus neoformans-Cryptococcus gattii complex is an important opportunistic infection in people with immunodeficiency, including in the haematology/oncology setting. ...

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