Our results suggest that maternal prenatal use of vitamins and folic acid reduces the risk of both ALL and AML ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

Teachers are responsible for children at school during peak ultraviolet (UV) times of the day. It is paramount that teachers have knowledge and understanding of UV to effectively protect themselves and their students. The aim of this pilot study was to investigate the effect of a short intervention on preservice teachers’ sun protective behaviours, knowledge and perceived skill to teach sun safety. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

Naturally acquired anti-HPV-16 antibodies were associated with a decreased risk of subsequent infection and cervical abnormalities in women >25 years ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• August 2019

It is unknown whether parental occupational exposure to chemicals before during and after pregnancy increases the risk of acute lymphoblastic... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• November 2011

The number of tRNA isodecoders has increased dramatically in mammals, but the specific molecular and physiological reasons for this expansion remain elusive. To address this fundamental question we used CRISPR editing to knockout the seven-membered phenylalanine tRNA gene family in mice, both individually and combinatorially. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• April 2023

The mitochondrial genome encodes core subunits of the respiratory chain that drives oxidative phosphorylation and is, therefore, essential for energy conversion. Advances in high-throughput sequencing technologies and cryoelectron microscopy have shed light on the structure and organization of the mitochondrial genome and revealed unique mechanisms of mitochondrial gene regulation. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

The evolutionary acquisition of mitochondria has given rise to the diversity of eukaryotic life. Mitochondria have retained their ancestral α-proteobacterial traits through the maintenance of double membranes and their own circular genome. Their genome varies in size from very large in plants to the smallest in animals and their parasites. The mitochondrial genome encodes essential genes for protein synthesis and has to coordinate its expression with the nuclear genome from which it sources most of the proteins required for mitochondrial biogenesis and function. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

We conclude that the novel chocolate-based formulation of midazolam provides improved tolerability while remaining efficacious ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

Research priority setting activities in paediatric chronic disease cover many discipline areas and have elicited a broad range of topics ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• October 2018

Growing evidence supports a role for infection in the etiology of ALL and the involvement of immune systems suggests that vaccination may also play a role. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

A simple, clinically relevant model to reliably discriminate patients at high and lower risk of death in patients with malignant pleural mesothelioma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• April 2016

Higher levels of paternal dietary vitamin B12 were appeared to be associated with an increased risk of childhood ALL, with those in the highest tertile of... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• October 2014