Maternal occupational pesticide exposure during pregnancy and/or paternal occupational pesticide exposure around conception have been suggested to increase... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• March 2014

The evidence that accelerated fetal growth is associated with a modest increased risk of childhood ALL is strong and consistent with known biological... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

To date there have been relatively few studies on genetic determinants of susceptibility to neonatal infection and many of these have methodological... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• June 2013

The presence of membrane-bound organelles with specific functions is one of the main hallmarks of eukaryotic cells. Organelle membranes are composed of specific lipids that govern their function and interorganelle communication. Discoveries in cell biology using imaging and omic technologies have revealed the mechanisms that drive membrane remodeling, organelle contact sites, and metabolite exchange. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024

RNA-binding proteins and mitochondrial ribosomes have been found to be linchpins of mitochondrial gene expression in health and disease. The expanding repertoire of proteins that bind and regulate the mitochondrial transcriptome has necessitated the development of new tools and methods to examine their molecular functions. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

The aim of this pilot study was to test the feasibility and acceptability of a family carer intervention for carers of patients with high-grade glioma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• October 2018

his study aimed to determine how carer distress and psychological morbidity change over time following a patient's diagnosis of high-grade glioma ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

330,000 Italians arrived in Australia between 1945 and 1966, many on assisted passage schemes where the worker agreed to a 2 year unskilled employment contract. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

This report provides new insight into the functional specialization within the broad network of dendritic cells that are responsible for skin immunosurveillance ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

In this rhinovirus study, we first hypothesized that ex vivo human cells response to virus can serve as a proxy for otherwise controversial in vivo human... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

Platelets are anucleate blood cells that contain mitochondria and regulate blood clotting in response to injury. Mitochondria contain their own gene expression machinery that relies on nuclear-encoded factors for the biogenesis of the oxidative phosphorylation system to produce energy required for thrombosis. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Directed evolution emulates the process of natural selection to produce proteins with improved or altered functions. These approaches have proven to be very powerful but are technically challenging and particularly time and resource intensive. To bypass these limitations, we constructed a system to perform the entire process of directed evolution in silico. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022