Epigenetic modifications are associated with hepatic fat accumulation and non-alcoholic fatty liver disease (NAFLD). However, few epigenetic modifications directly implicated in such processes have been identified during adolescence, a critical developmental window where physiological changes could influence future disease trajectory. To investigate the association between DNA methylation and NAFLD in adolescence, we undertook discovery and validation of novel methylation marks, alongside replication of previously reported marks. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• February 2023

Fetal alcohol spectrum disorder (FASD) is an umbrella term to describe a range of effects from prenatal alcohol exposure including fetal alcohol syndrome (FAS). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• September 2013

To identify and characterise appropriate comparison groups for population studies of health outcomes in ART-conceived births: ovulation induction (OI), subfertile untreated and fertile natural conceptions. Our secondary objective was to examine whether known risks of pregnancy complications and adverse birth outcomes in ART births are elevated in comparison with subfertile (untreated and OI) conception groups. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

Visual motor integration and handwriting skills were often impaired in this population of young people in a youth detention centre ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• December 2018

The current effectiveness trial evaluated the combination of a whole-school program designed to prevent bullying perpetration and victimization ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• May 2020

We describe a series of 6 cases where adoption of a low carbohydrate diet in children impacted growth and cardiovascular risk factors with potential long-term sequelae. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• April 2017

Food allergy is mediated by a combination of genetic and environmental risk factors, potentially mediated by epigenetic mechanisms. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• July 2014

This study aimed to elucidate how an adverse prenatal environment, as defined by the presence of a number of known prenatal risk factors, would influence... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

Our data provide insight into the molecular mechanisms underpinning the association of HLA-DRB1 alleles with risk versus protection in visceral leishmaniasis in humans ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• April 2018

Increases in ASD was not only limited to advancing paternal or maternal age alone but also to differences parental age including younger or older similarly age ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• May 2016

To establish baseline prevalence of neural tube defects (NTDs) prior to mandatory folic acid fortification in Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• August 2010

Association of pre-pregnancy weight, birth defects ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• April 2010