In this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• December 2015

Using data from three large-scale genetic association studies we compared recruitment strategy and sample return rates. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• May 2013

Adults living in the sunny Australian climate are at high risk of skin cancer, but vitamin D deficiency (defined here as a serum 25-hydroxyvitamin D... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

Gina Matt Trapp Cooper GT MC BHSc(Hons1A), RPHNutr, PhD BCA Marketing, BSc Statistics and Applied Statistics, PhD ARC DECRA Fellow & Head of Food and Nutrition Research Manager, Biometrics 0410 589 374 08 6319 1723 Gina.Trapp@telethonkids.org.au ...

• 1. Telethon Kids Institute
• Projects

The immediate-early response mediates cell fate in response to a variety of extracellular stimuli and is dysregulated in many cancers. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Several studies suggest that maternal folic acid supplementation before or during pregnancy protects against childhood acute lymphoblastic leukaemia (ALL). ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Bacille Calmette-Guérin (BCG) is the most commonly administered vaccine in human history. The medical application of BCG extends far beyond the fight against tuberculosis. Despite its stellar medical record over 100 years, insight into how BCG provides this vast range of benefits is largely limited, both for its pathogen-specific (tuberculosis) as well as pathogen-agnostic (other infections, autoimmunity, allergies, and cancer) effects. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

The methylation variation in the promoter region of CD14 gene did not explain the asthma and allergy contrast between Finnish and Russian Karelian children ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• November 2016

Our findings suggest that prenatal exposure to inflammation may alter the risk of sepsis in preterm infants partly by modulation of monocyte responses to pathogens ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• September 2018

Neonatal sepsis remains one of the key challenges of neonatal medicine, and together with preterm birth, causes almost 50% of all deaths globally for children younger than 5 years. Compared with advances achieved for other serious neonatal and early childhood conditions globally, progress in reducing neonatal sepsis has been much slower, especially in low-resource settings that have the highest burden of neonatal sepsis morbidity and mortality. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• June 2024

Biodiesel usage is increasing steadily worldwide as the push for renewable fuel sources increases. The increased oxygen content in biodiesel fuel is believed to cause decreased particulate matter (PM) and increased nitrous oxides within its exhaust. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• September 2022

The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and function are unknown. Suppressor of cytokine signaling (SOCS)1 and SOCS3 block STAT3, and low SOCS1 levels have been reported in IPF fibroblasts and shown to facilitate collagen production. Fibroblasts and lung tissue from IPF patients and controls were used to examine the mechanisms underlying SOCS1 down-regulation in IPF. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• April 2021