Combination vaccines containing whole-cell pertussis antigens were phased out from the Australian national immunisation programme between 1997 and 1999 and replaced by the less reactogenic acellular pertussis (aP) antigens. In a large case-control study of Australian children born during the transition period, those with allergist diagnosed IgE-mediated food allergy were less likely to have received whole-cell vaccine in early infancy than matched population controls (OR: 0.77 (95% CI, 0.62 to 0.95)). We hypothesise that a single dose of whole-cell vaccine in early infancy is protective against IgE-mediated food allergy. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• December 2020

The monoclonal antibody, palivizumab is licensed for use in high-risk infants to prevent severe illness caused by respiratory syncytial virus (RSV). The level of its use and compliance with current jurisdictional guidelines which were amended in 2010, is unknown. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• October 2020

Multi-jurisdictional cohort of mother-infant pairs to measure the uptake, safety and effectiveness of antenatal IIV and dTpa vaccines in three Australian jurisdictions ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• June 2019

This study evaluated for a multifactor structure in the DASS-21 teenagers and the specifics of the 3 subscales for teenagers in general at different stages. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

Determine the frequency of detection of specific viral pathogens in children with febrile seizures ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• December 2016

This study aimed to measure the effectiveness of three interventions designed to increase the duration of breastfeeding among new parents in urban areas. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• August 2015

Asthma is among the commonest noncommunicable diseases of childhood and often occurs with other atopic comorbidities. A previous case-control study found evidence that compared to children who received acellular pertussis (aP) vaccines in early infancy, children who received one or more doses of whole-cell pertussis (wP) vaccine had lower risk of developing IgE-mediated food allergy. We hypothesized that wP vaccination in early infancy might protect against atopic asthma in childhood.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• October 2023

Hayley Andrea Christian Nathan HC AN BSc (1st Class Hons), PhD W.Aust. BHlthSc (hons), PhD Program Head, Healthy Behaviours and Environments; National Heart Foundation Future Leader Fellow Senior Research Officer, PLAYCE 08 6319 1040 +61 8 6319 1045 ...

• 1. Telethon Kids Institute
• Projects

We did a systematic literature search to identify observational and/or interventional studies reporting cross-protection of TIV and A(H1N1)pdm09... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• March 2012

We introduce and describe the concept of a Rare Disease Registry and Analytics Platform ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

We found a numerically higher rate of preterm births among women who received 23vPPV in pregnancy compared to unvaccinated pregnant women ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020

A review of cases informed a change from a "3 + 0" infant schedule to a "2 + 1" schedule ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• February 2020