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        Parent-reported health-related quality of life of children with Down syndrome: A descriptive study

        To describe health-related quality of life of Australian children and adolescents with Down syndrome and compare it with norm-referenced data. ...

        Research

        Burkholderia pseudomallei evades Nramp1 (Slc11a1)- and NADPH oxidase-mediated killing in macrophages and exhibits Nramp1-dependent virulence gene expression

        Here we show that transfected macrophages stably expressing wild-type Nramp1 (Nramp1+) control the net replication of B. thailandensis, but not B. pseudomallei. ...

        Research

        Physician training programs significantly improve diagnosis in cases coded as anaphylaxis over time: A major factor compounding time-trend data?

        We conducted an investigation of all cases coded as anaphylaxis presenting to the main tertiary PED in Perth, Australia, where all coding is performed by staff. ...

        Research

        Breastfeeding beyond the big smoke: Who provides support for mothers in rural Western Australia?

        Antenatal group education is effective in supporting breastfeeding duration for rural women and should be a key priority for rural health service providers. ...

        Research

        Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI

        This study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease ...

        Research

        The bioenergetics of inflammation: insights into obesity and type 2 diabetes

        Diabetes mellitus is one of the most common chronic metabolic disorders worldwide, and its incidence in Asian countries is alarmingly high. ...

        Research

        Prevalence and profile of Neurodevelopment and Fetal Alcohol Spectrum Disorder (FASD) amongst Australian Aboriginal children living in remote communities

        Early intervention services are needed to support developmentally vulnerable children in remote communities. ...

        Research

        An exposome perspective: Early-life events and immune development in a changing world

        Here we review the historical origins of exposome research and define a new concept, the metaexposome ...

        Research

        Clinical presentation of Attenuated Psychosis Syndrome in children and adolescents: Is there an age effect?

        Older age at presentation of Attenuated Psychosis Syndrome was associated with less functional impairment, but age was not associated with psychotic symptoms ...

        Research

        Clonal expansion of new penicillin-resistant clade of neisseria meningitidis serogroup w clonal complex 11, Australia

        In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016 ...

        Research

        CDKL5 variants: Improving our understanding of a rare neurologic disorder

        Providing new insights into the interpretation of genetic variants in a rare neurologi disorder, in the contexts of population sequencing data. ...

        Research

        Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes

        Results from this linked population study suggests that there are differences in maternal infection by virus type and support the provision of seasonal vaccines ...

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