Infant lung function (ILF) testing may provide useful information about lung growth and susceptibility to respiratory disease. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• December 2013

There is limited information on changes in FOT outcomes in healthy children beyond the preschool years and the level of bronchodilator responsiveness (BDR)... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• July 2013

Unsedated infant lung function measures of tidal breathing, MBW, and eNO are feasible in a semi-rural African setting ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• December 2014

Current treatments for respiratory infections are severely limited. Ethanol's unique properties including antimicrobial, immunomodulatory, and surfactant-like activity make it a promising candidate treatment for respiratory infections if it can be delivered safely to the airway by inhalation. Here, we explore the safety, tolerability, and pharmacokinetics of inhaled ethanol in a phase I clinical trial. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• March 2024

Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an invasive pleural model with a non-invasive subcutaneous model of mesothelioma and performed transcriptomic analyses on the tumour samples. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

To establish the burden of respiratory illness in cerebral palsy (CP) on the Western Australian health care system by quantifying the costs of respiratory hospitalizations in children with CP, compared with non-respiratory hospitalizations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• July 2023

Appropriate interpretation of pulmonary function tests (PFTs) involves the classification of observed values as within/outside the normal range based on a reference population of healthy individuals, integrating knowledge of physiological determinants of test results into functional classifications and integrating patterns with other clinical data to estimate prognosis. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Alexander Anthony Larcombe Kicic A A BScEnv (Hons) PhD BSc (Hons) PhD Team Leader, Respiratory Environmental Health Rothwell Family Fellow; Head, Airway Epithelial Research Anthony.Kicic@telethonkids.org.au Team Leader, Respiratory Environmental ...

• 1. Telethon Kids Institute
• Projects

HIV exposure is associated with altered lung function in early life, with a vulnerable HIV-exposed uninfected subgroup based on maternal disease severity ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• March 2020

Acinar ventilation inhomogeneity measured by single-breath washout was not associated with structural lung disease on CT ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• May 2019

Our data shows that the expression of distinct IFNα subtypes within the tumor microenvironment results in different anti-tumor activities ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

The review will outline evidence of long-term health effects, possible mechanisms linking burn injury to long-term health and current research into burns as a chronic disease ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• September 2019