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        49-60 of 678 results for 'CANCER'

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        Tissue resident memory T cells: putting cancer cells to sleep and a target for therapy

        Alison McDonnell AM BSc (Hons), PhD Early Career Fellow alison.mcdonnell@telethonkids.org.au Early Career Fellow Dr Alison McDonnell is a post-doctoral scientist with a research focus in cancer immunology. Following a PhD using preclinical models of ...

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        All-cause mortality and cancer incidence among adults exposed to blue asbestos during childhood

        This study investigated cancer and mortality of adults exposed to blue asbestos as children. ...

        Research

        Infant feeding practices and childhood acute leukemia: Findings from the Childhood Cancer & Leukemia International Consortium

        Increasing evidence suggests that breastfeeding may protect from childhood acute lymphoblastic leukemia and acute myeloid leukemia. However, most studies have limited their analyses to any breastfeeding, and only a few data have examined exclusive breastfeeding, or other exposures such as formula milk. ...

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        ‘Torn in two’: Experiences of Mothers Who Are Pregnant when Their Child Is Diagnosed With Cancer

        Mothers of children diagnosed with cancer have been shown to experience high rates of psychological distress and poor physical health. Pregnancy further increases the healthcare needs of mothers due to the marked physiological changes and psychological adaptations. ...

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        Population-level 5-year event-free survival for children with cancer in Australia

        Event-free survival considers other adverse events in addition to mortality. It therefore provides a more complete understanding of the effectiveness and consequences of treatment than standard survival measures, but is rarely reported at the population level for childhood cancer. ...

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        Time-course RNAseq data of murine AB1 mesothelioma and Renca renal cancer following immune checkpoint therapy

        Time-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood. Here, we present whole tumor RNA sequencing data in the context of treatment with ICB in murine models of AB1 mesothelioma and Renca renal cell cancer.  ...

        Research

        Caregiver burden, mutuality, and family resilience in colorectal cancer caring: A mediating model analysis

        This study investigates the interaction between caregiver burden, mutuality, and family resilience in colorectal cancer management, and determines whether mutuality affects the effect of caregiver burden on family resilience. ...

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        A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

        Molecular profiling of the tumour immune microenvironment (TIME) has enabled the rational choice of immunotherapies in some adult cancers. In contrast, the TIME of paediatric cancers is relatively unexplored. We speculated that a more refined appreciation of the TIME in childhood cancers, rather than a reliance on commonly used biomarkers such as tumour mutation burden (TMB), neoantigen load and PD-L1 expression, is an essential prerequisite for improved immunotherapies in childhood solid cancers. ...

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        Transcriptome analysis of recurrently deregulated genes across multiple cancers identifies new pan-cancer biomarkers

        Genomewide expression profiling approach identified a comprehensive set of candidate biomarkers with pan-cancer potential ...

        Research

        Serum levels of folate, lycopene, beta-carotene, retinol and vitamin E and prostate cancer risk

        Previous studies relating increased serum levels of folate and fat-soluble vitamins to prostate cancer risk have variously shown null associations or to either ...

        Research

        Targeting cross-presentation as a route to improve the efficiency of peptide-based cancer vaccines

        Cross-presenting dendritic cells (DC) offer an attractive target for vaccination due to their unique ability to process exogenous antigens for presentation on MHC class I molecules. Recent reports have established that these DC express unique surface receptors and play a critical role in the initiation of anti-tumor immunity, opening the way for the development of vaccination strategies specifically targeting these cells. ...

        Research

        Financial toxicity of informal caregivers of colorectal cancer patients: A cross-sectional study

        To assess the level of financial toxicity of informal caregivers of colorectal cancer patients and explore the related key influencing factors. ...

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