A hallmark of atopic asthma is development of chronic airways hyper-responsiveness (AHR) that persists in the face of ongoing exposure to perennial... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• May 2012

Alexander David Deborah Larcombe Martino Strickland A DM DH BScEnv (Hons) PhD BSc PhD PhD Team Leader, Respiratory Environmental Health Head, Clinical Epigenetics Program Head, Immunobiology and Immunotherapeutic Program David.Martino@ ...

• 1. Telethon Kids Institute
• Projects

Findings provide further proof of concept that pharmacological targeting of airway smooth muscle thickness will be beneficial and may be facilitated by azithromycin ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• June 2020

Early life rhinovirus infection influences the development of house-dust-mite induced lung disease in female, but not male mice ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

This study shows, for the first time, that exposure to e-cigarette aerosol during adolescence and early adulthood is not harmless to the lungs and can result in significant impairments in lung function. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• July 2017

Most asthmatics would prefer workplaces, healthcare facilities, and environments that are fragrance-free, which could help reduce adverse effects ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

There was a positive relationship between the thickness of the airway smooth muscle layer with airway responsiveness, which was shifted upward in the presence of allergy ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• February 2018

In this study we assessed the effects of antigen exposure in mice pre‐sensitized with allergen following viral infection on changes in lung function, cellular responses and tight junction expression. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• August 2021

Canola biodiesel exhaust exposure elicits inflammation and reduces viability of human epithelial cell cultures in vitro when compared with ULSD exhaust exposure ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Biodiesel is created through the transesterification of fats/oils and its usage is increasing worldwide as global warming concerns increase. Biodiesel fuel properties change depending on the feedstock used to create it. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

Immunological homeostasis in the respiratory tract is thought to require balanced interactions between networks of dendritic cell (DC) subsets in lung... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• November 2014

Here, we report on a model that does not use Th2-skewing adjuvants and yet achieves sensitization solely via the nasal mucosa. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• January 2012