This novel approach aimed to prevent inflated hazard ratios arising from reverse causation, and allow identification of associations beyond those already... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015

Increasing evidence suggests that breastfeeding may protect from childhood acute lymphoblastic leukemia and acute myeloid leukemia. However, most studies have limited their analyses to any breastfeeding, and only a few data have examined exclusive breastfeeding, or other exposures such as formula milk. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• May 2022

Mothers of children diagnosed with cancer have been shown to experience high rates of psychological distress and poor physical health. Pregnancy further increases the healthcare needs of mothers due to the marked physiological changes and psychological adaptations. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022

This study investigated cancer and mortality of adults exposed to blue asbestos as children. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an invasive pleural model with a non-invasive subcutaneous model of mesothelioma and performed transcriptomic analyses on the tumour samples. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• May 2023

Nick Gottardo NG MBChB FRACP PhD Co-Head, Brain Tumour Research nicholas.gottardo@telethonkids.org.au Co-Head, Brain Tumour Research Professor Nick Gottardo co-leads the Brain Tumour Research Programme at the Telethon Kids Institute. He is also Head ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

To assess the level of financial toxicity of informal caregivers of colorectal cancer patients and explore the related key influencing factors. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

Cross-presenting dendritic cells (DC) offer an attractive target for vaccination due to their unique ability to process exogenous antigens for presentation on MHC class I molecules. Recent reports have established that these DC express unique surface receptors and play a critical role in the initiation of anti-tumor immunity, opening the way for the development of vaccination strategies specifically targeting these cells. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Previous studies relating increased serum levels of folate and fat-soluble vitamins to prostate cancer risk have variously shown null associations or to either ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• October 2010

Genomewide expression profiling approach identified a comprehensive set of candidate biomarkers with pan-cancer potential ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• January 2016

Time-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood. Here, we present whole tumor RNA sequencing data in the context of treatment with ICB in murine models of AB1 mesothelioma and Renca renal cell cancer.  ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• May 2024

Event-free survival considers other adverse events in addition to mortality. It therefore provides a more complete understanding of the effectiveness and consequences of treatment than standard survival measures, but is rarely reported at the population level for childhood cancer. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• July 2024