These observations suggest factors in the modern environment promote pancreatic islet autoimmunity and destruction of insulin-producing beta cells. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• August 2013

Studies examining associations of early-life cat and dog ownership with childhood asthma have reported inconsistent results. Several factors could explain these inconsistencies, including type of pet, timing, and degree of exposure. Our aim was to study associations of early-life cat and dog ownership with asthma in school-aged children, including the role of type (cat vs dog), timing (never, prenatal, or early childhood), and degree of ownership (number of pets owned), and the role of allergic sensitization. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• February 2022

Liz Tim Davis Jones EA TW MBBS FRACP PhD MBBS DCH FRACP MD Head, Chronic & Severe Diseases Research Focus Area; Clinical Lead, Diabetes and Obesity Research Co-head, Diabetes and Obesity Research Head, Chronic & Severe Diseases Research Focus Area; ...

• 1. Telethon Kids Institute
• Our research
• Chronic and Severe Diseases
• Diabetes, Metabolism and Clinical Sciences
• Diabetes and Obesity Research
• Expired Projects

Severe winter lower respiratory infections in early life are known to be major risk factors for subsequent development of asthma, and it is also known that the high susceptibility to these infections in infants is due to the functional immaturity of ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Human Immunology

The Lililwan Project was the first Australian population-based prevalence study of fetal alcohol spectrum disorder (FASD) using active case ascertainment. Conducted in 2010-2011, the study included 95% of all eligible children aged 7-9 years living in the very remote Aboriginal communities of the Fitzroy Valley, Western Australia. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

Appropriate use of antibiotics is life-saving in neonatal early-onset sepsis (EOS), but overuse of antibiotics is associated with antimicrobial resistance and long-term adverse outcomes. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• November 2022

The human gut microbiome has increasingly been associated with autism spectrum disorder (ASD), which is a neurological developmental disorder, characterized by impairments to social interaction. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

Strategies to prevent early-life food allergen sensitisation prior to commencement of solid foods are needed and should be the focus of future research ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

Nutrition is one of the most easily modifiable environmental factors during early life that may play a role in allergic disease prevention. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• January 2017

There is a growing understanding that chronic respiratory diseases in adults have their origins in early life ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• August 2010

Onco-fetal reprogramming of the tumor ecosystem induces fetal developmental signatures in the tumor microenvironment, leading to immunosuppressive features. Here, we employed single-cell RNA sequencing, spatial transcriptomics and bulk RNA sequencing to delineate specific cell subsets involved in hepatocellular carcinoma  relapse and response to immunotherapy.  ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• January 2024

The effect of prenatal life stress on BP was accentuated by a higher BMI. Fetal programming events as a result of prenatal stress may underpin some of these... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• April 2015