Dysbiosis refers to a reduction in microbial diversity, combined with a loss of beneficial taxa, and an increase in pathogenic microorganisms. Dysbiosis of the intestinal microbiota can have a substantial effect on the nervous and immune systems, contributing to the onset of several inflammatory diseases. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• September 2021

Alanna Neida Tess Sincovich Sechague Monroy Gregory AS NSM TG BPsych(Hons), PhD BDS, MPH BSc (Hons), PhD (Psychology) Senior Research Officer Research Assistant Senior Research Fellow 08 6375 6108 +61 8 6375 6113 Alanna.sincovich@ ...

• Telethon Kids Institute
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Alexander Pat Deborah Larcombe Holt Strickland A PG DH BScEnv (Hons) PhD PhD, DSc, FRCPath, FRCPI, FAA PhD Team Leader, Respiratory Environmental Health Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic Program ...

• Telethon Kids Institute
• Our research
• Early Environment
• Immunobiology & Immunotherapeutic Program
• Pregnancy and Early Life Immunology

The associations between childhood acute lymphoblastic leukemia (ALL) and several proxies of early stimulation of the immune system, that is, day-care center... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

The dramatic rise in early childhood allergic diseases indicates the specific vulnerability of the immune system to early life environmental changes. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Although debate surrounding the mechanism or mechanisms governing this causal pathway remains intense, demonstration of the capacity of pretreatment... ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• May 2015

Amy Bec Finlay-Jones Young AFJ BY BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BSc Nursing, Grad Cert Clinical Nursing, M Mental Health Nursing Head, Early Neurodevelopment & Mental Health; Healthway WA Senior Research Fellow ...

• Telethon Kids Institute
• Projects

Delays within the motor domain are often overlooked as an early surveillance marker for autism. The present study evaluated motor difficulties and its potential as an early predictive marker for later autism likelihood in a cohort of infants showing early behavioral signs of autism aged 9-14 months. The motor domain was evaluated using the motor subscales of the Mullen Scales of Early Learning at baseline, and at a 6-month follow-up. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• May 2021

the association between infant LRTI and risk for persistent wheeze/asthma in this cohort is generally stronger for fLRTIs than for other infection categories ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• November 2019

The dramatic increase in the prevalence of allergic disease in recent decades reflects environmental and behavioural changes that have altered patterns of early immune development. The very early onset of allergic diseases points to the specific vulnerability of the developing immune system to environmental changes and the development of primary intervention strategies is crucial to address this unparalleled burden. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• April 2022

Results from recent clinical studies suggest potential efficacy of immune training (IT)-based approaches for protection against severe lower respiratory tract infections in infants, but underlying mechanisms are unclear. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• July 2022

The co-exposure responses in the Th2high BN incorporated type I interferon/Th1, alternative macrophage activation/Th2 and Th17 signatures ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018