Rheumatic heart disease (RHD) after group A streptococcus (GAS) infections is heritable and prevalent in Indigenous populations. Molecular mimicry between human and GAS proteins triggers proinflammatory cardiac valve-reactive T cells. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• December 2017

This paper reviews American cutaneous leishmaniasis (ACL) immunogenetics in the state of Bahia (BA), northeastern Brazil, highlighting the interacting roles... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• May 2014

Diffuse midline glioma (DMG), including tumors diagnosed in the brainstem (diffuse intrinsic pontine glioma; DIPG), are uniformly fatal brain tumors that lack effective treatment. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2024
• February 2024

Scedosporium spp. are the second most prevalent filamentous fungi after Aspergillus spp. recovered from cystic fibrosis (CF) patients in various regions of the world. Although invasive infection is uncommon prior to lung transplantation, fungal colonization may be a risk factor for invasive disease with attendant high mortality post-transplantation. Abundant in the environment, Scedosporium aurantiacum has emerged as an important fungal pathogen in a range of clinical settings. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• December 2021

Based on population data from 5 countries, the heritability of ASD was estimated to be approximately 80% ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• July 2019

To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI),... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• February 2015

Visceral leishmaniasis (VL) is caused by Leishmania donovani and Leishmania infantum chagasi. Genome-wide linkage studies from Sudan and Brazil identified... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• March 2011

Interleukin-10 is a key immunomodulatory cytokine the principal function of which is to limit the magnitude of immune response. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• March 2011

Progress in psychiatric genetics has been slow despite evidence of high heritability for most mental disorders ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2011
• January 2011

Jenefer Timo Blackwell Lassmann JM T BSc with First Class Honours, PhD, DSc, FMedSci, FAA BSc (Hons) MSc PhD Head, Genetics & Health Feilman Fellow; Program Head, Precision Health and Team Lead, Computational Biology Jenefer.Blackwell@ ...

• 1. Telethon Kids Institute
• Our research
• Past teams
• Genetics and Health

GWAS analyses of allergic sensitization against inhalant allergens and nonallergic rhinitis suggested shared genetic mechanisms across rhinitis-related traits ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

Globally, there is a recognised need that all populations should be able to access the benefits of genomics and precision medicine. However, achieving this remains constrained by a paucity of data that quantifies access to clinical genomics, particularly amongst Indigenous populations. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022