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        Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM-85

        The effects of OM-85 were strongest in the first winter season, with a trend for fewer children in the OM-85 group to have sLRIs and URIs ...

        Research

        Streptococcus pneumoniae colonization of the nasopharynx is associated with increased severity during respiratory syncytial virus infection in young children.

        The present study aimed to clarify the effect of viral and bacterial co-detections on disease severity during paediatric ARI. ...

        Research

        Asthma is responsible for considerable global morbidity and health-care costs. Substantial progress was made against key outcomes such as hospital admissions with asthma and mortality in the 1990s and early 2000s, but little improvement has been observed

        We aim to provide our view of where we are and where we need to go as a community of clinicians and researchers who tackle the public health problem of asthma. ...

        Research

        Timing of routine infant vaccinations and risk of food allergy and eczema at one year of age

        There was no overall association between delayed DTaP and food allergy; however, children with delayed DTaP had less eczema and less use of eczema medication ...

        Research

        Environmental microbial exposure and protection against asthma

        This article looks at the clinical implications of the research into microbial exposure & protection against asthma. ...

        Research

        Genome-wide association study identifies peanut allergy-specific loci and evidence of epigenetic mediation in US children

        Food allergy (FA) affects 2%-10% of US children and is a growing clinical and public health problem. ...

        Research

        Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study

        This genome-wide association study (GWAS) utilises data from the Western Australian Pregnancy Cohort (Raine) Study for 25-hydroxyvitamin D (25(OH)D) levels... ...

        Research

        Vitamin D deficiency at 16 to 20 weeks' gestation is associated with impaired lung function and asthma at 6 years of age

        This paper examines whether a Vitamin D deficiency during pregnancy affects the child's lung function predisposition towards lung disease such as asthma. ...

        Research

        Defective respiratory tract immune surveillance in asthma : A primary causal factor in disease onset and progression

        The relative importance of respiratory viral infections vs inhalant allergy in asthma pathogenesis is the subject of ongoing debate. ...

        Research

        Persistent Effects of Maternal Smoking during Pregnancy on Lung Function and Asthma in Adolescents

        The extent to which maternal smoking in pregnancy (MSP) has persisting effects on respiratory health remains uncertain and the mechanisms involved are not... ...

        Research

        Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis

        Atopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic... ...

        Research

        Gene-vitamin D interactions on food sensitization: A prospective birth cohort study

        It has been hypothesized that vitamin D deficiency (VDD) contributes to the development of food sensitization (FS) and then food allergy. ...

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