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        Gene polymorphisms, breast-feeding, and development of food sensitization in early childhood

        The effect of breast-feeding on the development of allergic disease is uncertain ...

        Research

        World Allergy Organization (WAO) Diagnosis and Rationale for Action against Cow's Milk Allergy (DRACMA) guidelines update – X – Breastfeeding a baby with cow's milk allergy

        Cow's milk allergy is rare in exclusively breastfed infants. To support the continuation of breastfeeding an infant after diagnosis with a cow's milk allergy, it is critical to examine the evidence for and against any form of cow's milk elimination diet for lactating mothers. In this narrative review, we highlight the lack of high-quality evidence, hence subsequent controversy, regarding whether the minuscule quantities of cow's milk proteins detectable in human milk cause infant cow's milk allergy symptoms. ...

        Research

        Prebiotics: mechanisms and preventive effects in allergy

        In this review, we describe both the mechanisms and the therapeutic evidence from preclinical and clinical studies exploring the role of prebiotics in allergy prevention ...

        Research

        Propofol use in children with allergies to egg, peanut, soybean or other legumes

        We conclude that genuine serious allergic reaction to propofol is rare and is not reliably predicted by a history of food allergy ...

        Research

        Food Proteins in Human Breast Milk and Probability of IgE-Mediated Allergic Reaction in Children During Breastfeeding: A Systematic Review

        Previous reports suggested that food proteins present in human milk (HM) may trigger symptoms in allergic children during breastfeeding, but existing evidence has never been reviewed systematically. ...

        Research

        An Australian Consensus on Infant Feeding Guidelines to Prevent Food Allergy: Outcomes From the Australian Infant Feeding Summit

        Infant feeding in the first postnatal year of life has an important role in an infant's risk of developing food allergy ...

        Research

        Increased Use of Adrenaline in the Management of Childhood Anaphylaxis Over the Last Decade

        There was a significant improvement in the management of anaphylaxis after the introduction of intensified physician training programs ...

        Research

        Food for thought: progress in understanding the causes and mechanisms of food allergy

        Treatments for food allergy are still lacking, yet progress is being made, and immunotherapy appears more effective than dietary avoidance. ...

        Research

        Disease prevention in the age of convergence - The need for a wider, long ranging and collaborative vision

        Our global health crisis and the pandemic of noncommunicable diseases (NCDs) is clearly rooted in complex modern societal and environmental changes, many of... ...

        Research

        Probiotic peanut oral immunotherapy versus oral immunotherapy and placebo in children with peanut allergy in Australia (PPOIT-003): a multicentre, randomised, phase 2b trial

        Oral immunotherapy is effective at inducing desensitisation to allergens and induces sustained unresponsiveness (ie, clinical remission) in a subset of patients, but causes frequent reactions. We aimed to investigate whether addition of a probiotic adjuvant improved the efficacy or safety of peanut oral immunotherapy. ...

        Research

        Innate immune activation occurs in acute food protein–induced enterocolitis syndrome reactions

        Food reactions in food protein–induced enterocolitis syndrome are predominantly underpinned by activation of the innate immune system ...

        Research

        In-utero exposures and the evolving epidemiology of paediatric allergy

        This paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune... ...

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