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        A systematic approach to multiple breath nitrogen washout test quality

        The application of the systematic review improved inter-observer agreement but did not affect reported multiple breath washout outcomes ...

        Research

        Gut microbiome and innate immune response patterns in IgE-associated eczema

        Gut microbiome patterns have been associated with predisposition to eczema potentially through modulation of innate immune signalling. ...

        Research

        It takes a village to raise a child: The influence and impact of playgroups across Australia

        Comprehensive quantitative and qualitative evaluation of Community Playgroups across Australia ...

        Research

        Primary prevention of rheumatic fever in the 21st century: evaluation of a national programme

        Population-based primary prevention of ARF through sore throat management may be effective in well-resourced settings like New Zealand ...

        Research

        Structural determinants of long term functional outcomes in young children with cystic fibrosis

        Chest CT identifies children at an early age who have adverse long-term outcomes ...

        Research

        Functional genomics in cancer immunotherapy: Computational approaches for biomarker and drug discovery

        This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response ...

        Research

        In “high-risk” infants with sufficient vitamin d status at birth, infant vitamin D supplementation had no effect on allergy outcomes: A randomized controlled trial

        Early infancy oral vitamin D supplementation does not appear to reduce the development of early childhood allergic disease ...

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        Vaccine-preventable disease following allogeneic haematopoietic stem cell transplant in Western Australia

        There is a high incidence of vaccine-preventable morbidity post-allogeneic haematopoietic stem cell transplantation in West Australian children ...

        Research

        Outcomes and endpoints reported in studies of pulmonary exacerbations in people with cystic fibrosis: A systematic review

        There is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations in people with cystic fibrosis (CF). Outcomes used for evaluation should be meaningful; that is, they should capture how people feel, function or survive and be acknowledged as important to people with CF, or should be reliable surrogates of those outcomes. We aimed to summarise the outcomes and corresponding endpoints which have been reported in studies of pulmonary exacerbations, and to identify those which are most likely to be meaningful. ...

        Research

        Systematic assessment of tissue dissociation and storage biases in single-cell and single-nucleus RNA-seq workflows

        Systematic comparison of recovered cell types and their transcriptional profiles across the workflows has highlighted protocol-specific biase ...

        Research

        Effect of Fluoxetine on Obsessive-Compulsive Behaviors in Children and Adolescents With Autism Spectrum Disorders: A Randomized Clinical Trial

        Treatment with fluoxetine compared with placebo resulted in significantly lower scores for obsessive-compulsive behaviors at 16 weeks ...

        Research

        Preschool Multiple-Breath Washout Testing. An Official American Thoracic Society Technical Statement

        Consensus recommendations are outlined to direct preschool device design, test performance, and data analysis for the MBW technique ...

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