Ependymomas (EPN) are the third most common malignant brain cancer in children. Treatment strategies for pediatric EPN have remained unchanged over recent decades, with 10-year survival rates stagnating at just 67% for children aged 0-14 years. Moreover, a proportion of patients who survive treatment often suffer long-term neurological side effects as a result of therapy. It is evident that there is a need for safer, more effective treatments for pediatric EPN patients. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2023
• March 2023

Mary Brushe MB BPsych(Hons), PhD (Public Health) Senior Research Officer 08 6375 6102 mary.brushe@telethonkids.org.au Senior Research Officer @marybrushe she/her/hers Dr Brushe is a Senior Research Officer at Telethon Kids Institute whose research ...

• 1. Telethon Kids Institute
• Projects

André Schultz AS MBChB, PhD, FRACP Program Head, Respiratory Health RFA Program Head, Respiratory Health RFA Prof André Schultz is the Program Head of Respiratory Health and Head of the BREATH Team at Telethon Kids Institute. He is passionate ...

• 1. Telethon Kids Institute
• Projects

Melissa O'Donnell M BPsych (Hons), MPsych, GradDip Ed, PhD Honorary Research Associate Honorary Research Associate Areas of research expertise: Child maltreatment and linked cross-jurisdictional data. Associate Professor Melissa O'Donnell holds an ...

• 1. Telethon Kids Institute
• Projects

Australia's defence, infectious diseases ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2010
• November 2010

This study investigated the relapse and outcome patterns of patients with central nervous system mixed malignant germ cell tumors treated with chemotherapy-only ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• June 2015

Longitudinal analyses showed that for each increase in liquor stores over time, alcohol consumption increased ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• February 2017

We are living in a time of unprecedented risk for noncommunicable diseases (NCDs), such as obesity, cardiovascular disease, diabetes, cancer... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Allergic diseases are a major cause of morbidity in the developed world, now affecting up to 40 % of the population with no evidence that this is abating. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2015
• January 2015

Recurrent acute otitis media (AOM), frequently caused by Streptococcus pneumoniae, is a major paediatric health problem. ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

A double-blind, placebo-controlled clinical trial was conducted investigating the use of low-dose oral interferon alpha for preventing acute viral... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2013
• February 2013

Epidermal growth factor receptor (EGFR) is over-expressed in many brain tumors. This paper examines mutations the EGFR that make the cell it is produced in... ...

• 1. Telethon Kids Institute
• Our research
• Reports and Findings
• 2014
• April 2014