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        Updated model of group A Streptococcus M proteins based on a comprehensive worldwide study

        Group A Streptococcus (GAS) M protein is an important virulence factor and potential vaccine antigen, and constitutes the basis for strain typing (emm-typing). ...

        Research

        Group A streptococcal vaccines: Paving a path for accelerated development

        Vaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades. ...

        Research

        Bacillus Cereus Bacteremia and Multiple Brain Abscesses During Acute Lymphoblastic Leukemia Induction Therapy

        Bacillus cereus can cause serious infections in immunosuppressed patients. This population may be susceptible to B. cereus pneumonia, bacteremia, cellulitis,... ...

        Research

        Progress toward a global group a streptococcal vaccine

        The desire for an effective vaccine arises from the large burden of disease caused by the bacterium, particularly rheumatic fever and rheumatic heart disease. ...

        Research

        Preventing urinary tract infections in early childhood

        Urinary tract infection (UTI) is common in children, causes them considerable discomfort, as well as distress to parents and has a tendency to recur. ...

        Research

        A national prospective surveillance study of acute rheumatic fever in Australian children

        Acute rheumatic fever (ARF) is an important cause of heart disease in Indigenous people of northern and central Australia. ...

        Research

        Trough concentrations of vancomycin: Adult therapeutic targets are not appropriate for Children

        Despite the need for effective vancomycin therapy, there are few data guiding vancomycin monitoring in children. We reviewed retrospectively vancomycin use... ...

        Research

        Hospitalisation for bronchiolitis in infants is more common after elective caesarean delivery

        The authors previously reported an increased risk of hospitalisation for acute lower respiratory infection up to age 2 years in children delivered by... ...

        Research

        Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population data

        Kawasaki disease results from an abnormal immunological response to one or more infectious triggers. ...

        Research

        Detection of the rapid emergency of the H274 mutation associated with oseltamivir-resistance

        In 2009 a new swine-origin influenza virus A/H1N1 (A/H1N1 09) emerged, causing the century's first pandemic. ...

        Research

        Nasopharyngeal density of respiratory viruses in childhood pneumonia in a highly vaccinated setting: findings from a case-control study

        Detection of pneumonia-causing respiratory viruses in the nasopharynx of asymptomatic children has made their actual contribution to pneumonia unclear. We compared nasopharyngeal viral density between children with and without pneumonia to understand if viral density could be used to diagnose pneumonia. ...

        Research

        Human genetics of leishmania infections

        GWAS results provide firm confirmation for the importance of antigen presentation and the regulation of IFNγ in determining the outcome of Leishmania infections ...

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