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        Controlled human infection for vaccination against Streptococcus pyogenes (CHIVAS): Establishing a group A Streptococcus pharyngitis human infection study

        We review the Group A Streptococcus Human infection studies and present the study protocol for a dose-ranging inpatient study in healthy adults ...

        Research

        Functional genomics in cancer immunotherapy: Computational approaches for biomarker and drug discovery

        This review explores computational strategies to yield biological insight into the processes involved in the immunotherapeutic response ...

        Research

        Factors associated with adherence to antimicrobial stewardship after-hours

        Restricted antimicrobials acquired after-hours are not routinely antimicrobial stewardship adherent at the time of acquisition or the next standard working day ...

        Research

        Reduced heart rate variability in adults with autism spectrum disorder

        Our data suggest an overall dysregulation in resting autonomic activity in adults with autism spectrum disorder ...

        Research

        novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

        This study thus identified a novel small molecule that rapidly kills MLL-rearranged leukemia cells by targeting a metabolic vulnerability ...

        Research

        B Part of It School Leaver protocol: an observational study to assess the impact of a meningococcal serogroup B vaccine programme on carriage of Neisseria meningitidis

        This study will assess the impact of MenB vaccine (4CMenB) on carriage prevalence in school leavers in South Australia ...

        Research

        Still keen and committed: piloting an instrument for identifying positive veteran teachers

        Initial findings suggest the potential of the instrument in helping identifying positive veteran teachers within systems, as well as the voracity of the research approach ...

        Research

        Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood

        These data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course ...

        Research

        Gender-affirming hormones and surgery in transgender children and adolescents

        This Review explores the available published evidence on gender-affirming cross-sex hormone and surgical interventions in transgender children ...

        Research

        Upper Airway Pathology Contributes to Respiratory Symptoms in Children Born Very Preterm

        The upper airway may play a role in the respiratory symptoms experienced by some very preterm children and should be considered by clinicians ...

        Research

        Standardizing clinical care measures of rheumatic heart disease in pregnancy: A qualitative synthesis

        Pregnancy provides an opportunity to strengthen health system responses and address whole-of-life health for women with rheumatic heart disease ...

        Research

        Agreement between units of measure for paediatric antibiotic utilisation surveillance using hospital pharmacy supply data

        Agreement between the DDD and vial-based measures of use supports the use of DDD for select antibiotics that may be targeted by antimicrobial stewardship programs ...

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