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        Exploring the synthetic potential of a marine transaminase including discrimination at a remote stereocentre

        The marine transaminase, P-ω-TA, can be employed for the transamination from 1-aminotetralins and 1-aminoindanes with differentiation of stereochemistry at both the site of reaction and at a remote stereocentre resulting in formation of ketone products with up to 93% ee. While 4-substituents are tolerated on the tetralin core, the presence of 3- or 8-substituents is not tolerated by the transaminase. ...

        Research

        Barriers and enablers of health service utilisation for childhood skin infections in remote aboriginal communities of Western Australia

        Health service utilisation in this setting may be enhanced by improving general awareness of the significance of childhood skin infections ...

        Research

        Skin infections in Australian Aboriginal children: a narrative review

        The Australian National Healthy Skin Guideline summarises evidence-based treatment of impetigo, scabies and fungal infections in high burden settings ...

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        Panel 4: Recent advances in understanding the natural history of the otitis media microbiome and its response to environmental pressures

        Advances in understanding bacterial dynamics in the upper airway microbiome are driving development of microbiota-modifying therapies to prevent or treat disease ...

        Research

        We won't find what we don't look for: Identifying barriers and enablers of chronic wet cough in Aboriginal children

        Key barriers to effective management of chronic wet cough are limited training in chronic wet cough management combined with competing complexities ...

        Research

        Women Migrants in Western Australia: Case Studies of Resilience and Empowerment

        We propose that women migrants, through alliances and collaboration, cross borders of learning and work towards generating change and transformation ...

        Research

        Associations between ethnicity, social contact, and pneumococcal carriage three years post-PCV10 in Fiji

        Indigenous iTaukei had greater frequency and intensity of contact compared with Fijians of Indian Descent ...

        Research

        The Brain Basis of Comorbidity in Neurodevelopmental Disorders

        This review discusses early brain development and the etiological factors that may give rise to atypical developmental trajectories, along with neuroimaging insights ...

        Research

        Elastase Exocytosis by Airway Neutrophils Associates with Early Lung Damage in Cystic Fibrosis Children

        Protease elastase exocytosis by airway neutrophils occurs in all cystic fibrosis children, and its cellular measure correlates with early lung damage ...

        Research

        Vaccine-preventable disease following allogeneic haematopoietic stem cell transplant in Western Australia

        There is a high incidence of vaccine-preventable morbidity post-allogeneic haematopoietic stem cell transplantation in West Australian children ...

        Research

        Association between interpregnancy interval and adverse birth outcomes in women with a previous stillbirth: an international cohort study

        Conception within 12 months of a stillbirth was common and was not associated with increased risk of adverse outcomes in the subsequent pregnancy ...

        Research

        Skin Health Situational analysis to inform skin disease control programs for the Kimberley

        Asha Jonathan Bowen Carapetis AM AC JR BA MBBS DCH FRACP PhD GAICD OAM AM MBBS FRACP FAFPHM PhD FAHMS Head, Healthy Skin and ARF Prevention Executive Director; Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@telethonkids.org.au ...

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