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        Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis

        These findings indicate that early CF lung disease is characterized by an increased mucus burden and inflammatory markers without infection or structural lung disease ...

        Research

        Regular exposure to non-burning ultraviolet radiation reduces signs of non-alcoholic fatty liver disease in mature adult mice fed a high fat diet

        Frequent exposure to low levels of sunlight may reduce the severity of hepatic steatosis induced in older adults living in environments of high caloric intake ...

        Research

        Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight

        We find that DNA methylation in neonatal blood is associated with birthweight, with a difference in birthweight ranging from -183 to 178 grams per 10% increase in methylation ...

        Research

        Dendritic cells and cancer: From biology to therapeutic intervention

        In this review, we discuss the different subsets of tumor-infiltrating dendritic cells and their role in anti-tumor immunity ...

        Research

        Benefits of caseload midwifery to prevent fetal alcohol spectrum disorder: A discussion paper

        Drawing on previous research, caseload midwifery has potential to support the prevention of fetal alcohol spectrum disorder through continuity of care ...

        Research

        Statistical Analysis Plan for "An international study of isoelectric electroencephalography events in infants and young children during anesthesia for surgery"

        This Statistical Analysis Plan details the statistical procedures to be applied for the analysis of data for the multicenter electroencephalography study ...

        Research

        A microbiome case-control study of recurrent acute otitis media identified potentially protective bacterial genera

        We characterised the nasopharyngeal microbiome of these children in comparison to children with rAOM to identify potentially protective bacteria. ...

        Research

        Molecular-genetic profiling and high-throughput in vitro drug screening in NUT midline carcinoma-An aggressive and fatal disease

        Our data emphasize the heterogeneity of NMC and highlights genetic aberrations that could be explored to improve therapeutic strategies. ...

        Research

        We examined the impact of introducing a dedicated team to OPAT, to define the role of increased medical oversight in improving patient outcomes in this cohort.

        To evaluate the risk of stillbirth, PTB, and SGA as a proxy for FGR following exposure to one or more of these factors in a previous birth. ...

        Research

        A 15-Year Old Burmese Girl With Hemoptysis: A Case Report

        A 15 year old girl, born in Hakha, Myanmar, presented with 2 months of intermittent hemoptysis 3 years after immigrating to Australia, via Malaysia. ...

        Research

        Bullying and mental health amongst Australian children and young people with cystic fibrosis

        This study describes the peer bullying experiences of young people with CF, and examines associations between school bullying and the psychological well-being of these young people ...

        Research

        Pneumococcal responses are similar in Papua New Guinean children aged 3-5 years vaccinated in infancy with pneumococcal polysaccharide vaccine with or without prior pneumococcal conjugate vaccine, or without pneumococcal vaccination

        We studied in a non-randomized follow-up trial the persistence of pneumococcal immunity in children, 3-5 years of age, in community controls of a similar age. ...

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