This study aimed to (1) examine the strength of the association between mental disorders/mental health problems, risk behaviours and tobacco smoking among Australian adolescents, (2) compare rates of tobacco smoking among Australian adolescents with major depressive disorder, attention-deficit/hyperactivity disorder and/or conduct disorder in 2013/14 vs 1998, and (3) identify the extent to which an association between tobacco smoking and mental health problems among adolescents can be attributed to non-mental health risk factors. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2020
• April 2020

Our data demonstrate that CD8+XCR1neg DCs possess a unique pattern of endocytic receptors and a restricted TLR profile that is particularly enriched for TLR5 ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2019
• January 2019

The co-exposure responses in the Th2high BN incorporated type I interferon/Th1, alternative macrophage activation/Th2 and Th17 signatures ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• August 2018

The transition to motherhood can be challenging, especially for first-time mothers, and can accompany maternal distress. Social support—such as that offered by peers—can be important in assisting mothers to manage such distress. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• October 2022

There is a large volume of research on the persistence of advantage and disadvantage across generations. Intergenerational studies typically address family resources as independent factors, which ignores how risks cluster together and accumulate over time. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• March 2022

Treatment for pulmonary exacerbations of cystic fibrosis (CF) can produce a range of positive and negative outcomes. Understanding which of these outcomes are achievable and desirable to people affected by disease is critical to agreeing to goals of therapy and determining endpoints for trials. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• January 2022

Incomplete maturation of immune regulatory functions at birth is antecedent to the heightened risk for severe respiratory infections during infancy. Our forerunner animal model studies demonstrated that maternal treatment with the microbial-derived immune training agent OM-85 during pregnancy promotes accelerated postnatal maturation of mechanisms that regulate inflammatory processes in the offspring airways. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2021
• July 2021

The demonstrated higher risks in young people for continued harm or possible death support the need for ongoing initiatives to reduce self-harm ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2016
• September 2016

Modulation of ASL pH has been proposed as a therapy for CF. However, evidence that ASL pH is reduced in CF is limited and conflicting. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2017
• November 2017

This study describes the peer bullying experiences of young people with CF, and examines associations between school bullying and the psychological well-being of these young people ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2018
• January 2018

We aimed to measure the antibody development to 2 bacteria in a birth cohort at high risk of allergic disease, and to assess which responses are asthma-linked. ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2012
• April 2012

Graham Kathryn Rachel Alana Hall Ramsey Foong Harper GL KR RF AH BAppSci PhD CRFS FANZSRS FThorSoc FERS BSc (Hons), PhD BSc (hons), PhD, MBiostat BSc (hons) Honorary Research Associate Co-Head, Children's Lung Health Senior Research Fellow Program ...

• Telethon Kids Institute
• Our research
• Reports and Findings
• 2022
• August 2022